Clinical trial Recruiting at 1 site Observational Ages 18 and up

Investigating Exosomes in Pancreatic Cancer Progression

Official title: Role of Exosomes in Pancreatic Cancer Progression

Run by IRCCS Azienda Ospedaliero-Universitaria di Bologna · NCT06777030 · Data updated 2026-11-12

This study is trying to find out if certain markers in the blood and urine of pancreatic cancer patients can help us understand how the disease progresses and identify new ways to diagnose it.

More Pancreatic Cancer trials

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment60 (estimated)
SponsorIRCCS Azienda Ospedaliero-Universitaria di Bologna
Academic / other
Locations1 site (Bologna)
StatusRecruiting
StartedMay 22, 2022
Main results expectedDecember 31, 2026
Study endsApril 30, 2027
Registry record updatedJanuary 15, 2025
Trial IDNCT06777030 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adults aged 18 and older who have been diagnosed with pancreatic cancer.

Probably not a fit

Patients who cannot undergo endoscopy with biopsy sampling or have other active neoplastic diseases may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This pilot study aims to identify circulating markers in the blood and urine of patients with pancreatic cancer and their association with disease stage. It will involve a cross-sectional analysis of tumor tissue, blood, and urine samples to characterize the content of extracellular vesicles/exosomes. The study will also explore the mechanisms of epithelial-mesenchymal transition and tumor aggressiveness to find potential predictive and diagnostic markers for pancreatic cancer.

Why it matters

Potential benefit: If successful, this study could lead to the development of new diagnostic markers for early detection of pancreatic cancer.

How similar studies have gone: While this approach is exploratory, similar studies investigating exosomes in cancer have shown promise, indicating potential for success.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion criteria:

* People with pancreatic cancer
* 18 years old
* Obtaining informed consent.

Exclusion criteria:

* Patients who do not need or cannot perform endoscopy with biopsy sampling;
* patients with a previous or active neoplastic pathology, different from pancreatic neoplasia.

Where it's running

  • IRCCS Azienda Ospedaliero-Universitaria di Bologna
    Bologna, Italy
    Recruiting

Study contacts

  • Principal investigator: Leonardo Henry Umberto Eusebi, MD — IRCCS Azienda Ospedaliero-Universitaria di Bologna
  • Study coordinator: Leonardo Henry Umberto Eusebi, MD
  • Email: leonardo.eusebi@unibo.it
  • Phone: 0039 0512143338

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.