Investigating environmental factors in male congenital testicular conditions
Role of the Environment and Endocrine Disruptors in Child Cryptorchidism
This study is trying to see if certain environmental factors, like chemicals, are linked to the occurrence of undescended testicles in baby boys.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 1452 (estimated) |
| Ages | 1 Month to 18 Years |
| Sex | Male |
| Sponsor | University Hospital, Montpellier Academic / other |
| Locations | 1 site (Montpellier) |
| Trial ID | NCT04342026 on ClinicalTrials.gov |
What this trial studies
This observational study aims to explore the potential association between environmental exposures, particularly endocrine disruptors, and the occurrence of cryptorchidism in male newborns. Cryptorchidism is a common congenital defect that can lead to serious health issues, including fertility disorders and cancer. The study will involve measuring the exposure of parents of male children with and without cryptorchidism to various environmental factors. By identifying potential environmental contributors, the research seeks to enhance understanding of this condition and inform public health strategies.
Who should consider this trial
Good fit: Ideal candidates for this study are parents of male children aged from the neonatal period to 18 years who have been diagnosed with cryptorchidism.
Not a fit: Patients who may not benefit from this study include those whose children do not have endocrine diseases or associated genital or urinary defects.
Why it matters
Potential benefit: If successful, this study could lead to improved prevention strategies for cryptorchidism and related health issues in male children.
How similar studies have performed: Other studies have suggested potential links between environmental factors and cryptorchidism, but this specific approach focusing on endocrine disruptors is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion criteria: \- Parents of male children from the neonatal period to 18 years of age (during surgery) with cryptorchidism Exclusion criteria: * Parents of children without endocrine disease. (adrenal, hypothalamic-pituitary, phosphocalcic, thyroid, diabetes, etc.) * Parents of children without an associated genital or urinary defect (hypospadias, micropenis, renal and bladder abnormalities) * Testicular Ectopia (testis outside of normal migration path) * Anorchidism and evanescent testicles, united or bilateral * Abnormalities of the abdominal wall (laparoschisis, omphalocele, Prune Belly) * Cryptorchidism integrating in the context of a polymalformative syndrome, including neurological.
Where this trial is running
Montpellier
- University hospital of Montpellier — Montpellier, France (Recruiting)
Study contacts
- Study coordinator: Nicolas KALFA, MD
- Email: n-kalfa@chu-montpellier.fr
- Phone: 00334 67 33 87 84
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.