Investigating environmental factors in male congenital testicular conditions
Official title: Role of the Environment and Endocrine Disruptors in Child Cryptorchidism
Run by University Hospital, Montpellier · NCT04342026 · Data updated 2026-11-12
This study is trying to see if certain environmental factors, like chemicals, are linked to the occurrence of undescended testicles in baby boys.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 1 Month to 18 Years |
| Sex | Men only |
| Enrollment | 1452 (estimated) |
| Sponsor | University Hospital, Montpellier Academic / other |
| Locations | 1 site (Montpellier) |
| Status | Recruiting |
| Started | April 16, 2020 |
| Main results expected | October 15, 2027 |
| Study ends | April 15, 2028 |
| Registry record updated | October 3, 2025 |
| Trial ID | NCT04342026 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are parents of male children aged from the neonatal period to 18 years who have been diagnosed with cryptorchidism.
✕Probably not a fit
Patients who may not benefit from this study include those whose children do not have endocrine diseases or associated genital or urinary defects.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to explore the potential association between environmental exposures, particularly endocrine disruptors, and the occurrence of cryptorchidism in male newborns. Cryptorchidism is a common congenital defect that can lead to serious health issues, including fertility disorders and cancer. The study will involve measuring the exposure of parents of male children with and without cryptorchidism to various environmental factors. By identifying potential environmental contributors, the research seeks to enhance understanding of this condition and inform public health strategies.
Why it matters
Potential benefit: If successful, this study could lead to improved prevention strategies for cryptorchidism and related health issues in male children.
How similar studies have gone: Other studies have suggested potential links between environmental factors and cryptorchidism, but this specific approach focusing on endocrine disruptors is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion criteria: \- Parents of male children from the neonatal period to 18 years of age (during surgery) with cryptorchidism Exclusion criteria: * Parents of children without endocrine disease. (adrenal, hypothalamic-pituitary, phosphocalcic, thyroid, diabetes, etc.) * Parents of children without an associated genital or urinary defect (hypospadias, micropenis, renal and bladder abnormalities) * Testicular Ectopia (testis outside of normal migration path) * Anorchidism and evanescent testicles, united or bilateral * Abnormalities of the abdominal wall (laparoschisis, omphalocele, Prune Belly) * Cryptorchidism integrating in the context of a polymalformative syndrome, including neurological.
Where it's running
-
University hospital of Montpellier
Montpellier, France Recruiting
Study contacts
- Study coordinator: Nicolas KALFA, MD
- Email: n-kalfa@chu-montpellier.fr
- Phone: 00334 67 33 87 84
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Comparing two surgical techniques for undescended testis treatment
This study is testing which surgical method works better to help boys with undescended testicles get them to move down into the scrotum during treatment.
-
Comparing two surgical methods for fixing an undescended testicle in boys
This study is testing which of two surgical methods works better for fixing an undescended testicle in boys and how it affects their health and quality of life afterward.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.