Investigating early oral aging in children

Childhood Early Oral Aging Syndrome: Prevalence, Associated Etiological Factors, and Consequences on Vertical Dimension of Occlusion (VDO): A Cross-Sectional Study

Observational University of Nove de Julho · NCT06381414

This study looks at how health problems and lifestyle choices affect tooth wear in young children aged 3 to 6 who are getting dental care.

Quick facts

Study typeObservational
Enrollment183 (estimated)
Ages3 Years to 6 Years
SexAll
SponsorUniversity of Nove de Julho Academic / other
Locations1 site (São Paulo, São Paulo)
Trial IDNCT06381414 on ClinicalTrials.gov

What this trial studies

This observational study focuses on the Early Oral Aging Syndrome (EOAS), which examines how systemic diseases and lifestyle factors contribute to oral health changes in young children. It aims to assess the prevalence and severity of early childhood tooth wear using a specific diagnostic index. Participants aged 3 to 6 years, who are receiving dental care at the University Nove de Julho, will be evaluated to identify factors associated with varying levels of tooth wear. The study seeks to enhance understanding of oral health issues in the pediatric population.

Who should consider this trial

Good fit: Ideal candidates for this study are children aged 3 to 6 years with complete deciduous teeth who are enrolled in dental care at the Uninove pediatric dentistry clinic.

Not a fit: Children with amelogenesis or dentinogenesis imperfecta, those undergoing orthodontic treatment, or those with genetic syndromes may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved early detection and management of oral health issues in children, enhancing their quality of life.

How similar studies have performed: While the concept of oral aging is being explored, this specific approach to studying early oral aging in children is relatively novel and has not been extensively tested in prior studies.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Children from three to six years of age with complete deciduous teeth;
* Children regularly enrolled for dental care at the Uninove pediatric dentistry clinic

Exclusion Criteria:

* Children with amelogenesis or dentinogenesis imperfecta
* Children undergoing orthodontic treatment
* Children with a genetic syndrome

Where this trial is running

São Paulo, São Paulo

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Aging
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.