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Clinical trial Recruiting at 1 site Observational Ages 3 to 6

Investigating early oral aging in children

Official title: Childhood Early Oral Aging Syndrome: Prevalence, Associated Etiological Factors, and Consequences on Vertical Dimension of Occlusion (VDO): A Cross-Sectional Study

Run by University of Nove de Julho · NCT06381414 · Data updated 2026-11-12

This study looks at how health problems and lifestyle choices affect tooth wear in young children aged 3 to 6 who are getting dental care.

Quick facts

Study typeObservational
Ages3 Years to 6 Years
SexAll
Enrollment183 (estimated)
SponsorUniversity of Nove de Julho
Academic / other
Locations1 site (São Paulo, São Paulo)
StatusRecruiting
StartedMay 1, 2024
Main results expectedJanuary 31, 2025
Study endsJune 20, 2025
Registry record updatedNovember 18, 2024
Trial IDNCT06381414 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are children aged 3 to 6 years with complete deciduous teeth who are enrolled in dental care at the Uninove pediatric dentistry clinic.

Probably not a fit

Children with amelogenesis or dentinogenesis imperfecta, those undergoing orthodontic treatment, or those with genetic syndromes may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study focuses on the Early Oral Aging Syndrome (EOAS), which examines how systemic diseases and lifestyle factors contribute to oral health changes in young children. It aims to assess the prevalence and severity of early childhood tooth wear using a specific diagnostic index. Participants aged 3 to 6 years, who are receiving dental care at the University Nove de Julho, will be evaluated to identify factors associated with varying levels of tooth wear. The study seeks to enhance understanding of oral health issues in the pediatric population.

Why it matters

Potential benefit: If successful, this study could lead to improved early detection and management of oral health issues in children, enhancing their quality of life.

How similar studies have gone: While the concept of oral aging is being explored, this specific approach to studying early oral aging in children is relatively novel and has not been extensively tested in prior studies.

Who can join: the full rules

Show full inclusion / exclusion criteria 
Inclusion Criteria:

* Children from three to six years of age with complete deciduous teeth;
* Children regularly enrolled for dental care at the Uninove pediatric dentistry clinic

Exclusion Criteria:

* Children with amelogenesis or dentinogenesis imperfecta
* Children undergoing orthodontic treatment
* Children with a genetic syndrome

Where it's running

  • Nove de Julho University
    São Paulo, São Paulo, Brazil     Recruiting

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
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Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.