Clinical trial Recruiting at 1 site Interventional Ages 18 to 80

Investigating decision-making and CPAP adherence in sleep apnea patients

Official title: Effort-based Decision-making as a Possible Predictor of Poor Adherence to CPAP Treatment in Obstructive Sleep Apnea

Run by Istituti Clinici Scientifici Maugeri SpA · NCT04557293 · Data updated 2026-11-12

This study is testing how the way people make decisions affects their ability to stick with CPAP treatment for sleep apnea.

Quick facts

Study typeInterventional
Ages18 Years to 80 Years
SexAll
Enrollment64 (estimated)
SponsorIstituti Clinici Scientifici Maugeri SpA
Academic / other
Locations1 site (Pavia)
StatusRecruiting
StartedMarch 10, 2021
Main results expectedApril 30, 2026
Study endsApril 30, 2026
Registry record updatedNovember 18, 2025
Trial IDNCT04557293 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 18 and older diagnosed with obstructive sleep apnea.

Probably not a fit

Patients with a BMI of 35 or higher, significant cognitive impairment, or other complex sleep or psychiatric disorders may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study focuses on patients with obstructive sleep apnea (OSA) to explore the relationship between effort-based decision-making and adherence to Continuous Positive Airway Pressure (CPAP) treatment. It aims to assess cognitive functions, particularly how decision-making processes may affect patients' ability to adhere to CPAP therapy. Participants will undergo cognitive evaluations at the time of diagnosis and again after six months of CPAP use to identify any changes and correlations. The study includes a control group for comparative analysis.

Why it matters

Potential benefit: If successful, this study could improve adherence to CPAP therapy in patients with obstructive sleep apnea, leading to better health outcomes.

How similar studies have gone: While there have been studies on CPAP adherence, this specific focus on effort-based decision-making in relation to cognitive function is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age ≥ 18
* AHI±15

Exclusion Criteria:

* BMI ≥ 35 Kg/m2
* MMSE \<24
* Complex sleep apnoea
* Sleep disorder
* Psychiatric disorder

Where it's running

  • ICS Maugeri Pavia
    Pavia, Italy
    Recruiting

Study contacts

  • Principal investigator: Nicola Canessa, PhD — IRCCS Istituti Clinici Scientifici Maugeri - Scuola superiore IUSS Pavia
  • Study coordinator: Nicola Canessa, PhD
  • Email: nicola.canessa@icsmaugeri.it
  • Phone: +39 0382 375845

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.