Investigating decision-making and CPAP adherence in sleep apnea patients
Official title: Effort-based Decision-making as a Possible Predictor of Poor Adherence to CPAP Treatment in Obstructive Sleep Apnea
Run by Istituti Clinici Scientifici Maugeri SpA · NCT04557293 · Data updated 2026-11-12
This study is testing how the way people make decisions affects their ability to stick with CPAP treatment for sleep apnea.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 80 Years |
| Sex | All |
| Enrollment | 64 (estimated) |
| Sponsor | Istituti Clinici Scientifici Maugeri SpA Academic / other |
| Locations | 1 site (Pavia) |
| Status | Recruiting |
| Started | March 10, 2021 |
| Main results expected | April 30, 2026 |
| Study ends | April 30, 2026 |
| Registry record updated | November 18, 2025 |
| Trial ID | NCT04557293 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 18 and older diagnosed with obstructive sleep apnea.
✕Probably not a fit
Patients with a BMI of 35 or higher, significant cognitive impairment, or other complex sleep or psychiatric disorders may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study focuses on patients with obstructive sleep apnea (OSA) to explore the relationship between effort-based decision-making and adherence to Continuous Positive Airway Pressure (CPAP) treatment. It aims to assess cognitive functions, particularly how decision-making processes may affect patients' ability to adhere to CPAP therapy. Participants will undergo cognitive evaluations at the time of diagnosis and again after six months of CPAP use to identify any changes and correlations. The study includes a control group for comparative analysis.
Why it matters
Potential benefit: If successful, this study could improve adherence to CPAP therapy in patients with obstructive sleep apnea, leading to better health outcomes.
How similar studies have gone: While there have been studies on CPAP adherence, this specific focus on effort-based decision-making in relation to cognitive function is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age ≥ 18 * AHI±15 Exclusion Criteria: * BMI ≥ 35 Kg/m2 * MMSE \<24 * Complex sleep apnoea * Sleep disorder * Psychiatric disorder
Where it's running
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ICS Maugeri Pavia
Pavia, Italy Recruiting
Study contacts
- Principal investigator: Nicola Canessa, PhD — IRCCS Istituti Clinici Scientifici Maugeri - Scuola superiore IUSS Pavia
- Study coordinator: Nicola Canessa, PhD
- Email: nicola.canessa@icsmaugeri.it
- Phone: +39 0382 375845
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.