Investigating contact sensitization in allergic dermatitis using statistical and machine learning methods
A Prospective Study to Investigate Contact Sensitization Using Classic and Machine Learning Techniques
Andreas Syggros Hospital of Venereal and Dermatological Diseases · NCT05991674
This study is trying to see how different factors affect allergic contact dermatitis in patients by looking at data from patch tests.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 80 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Andreas Syggros Hospital of Venereal and Dermatological Diseases (other) |
| Locations | 1 site (Athens, Attica) |
| Trial ID | NCT05991674 on ClinicalTrials.gov |
What this trial studies
This observational study aims to explore the patterns of sensitization in patients with allergic contact dermatitis (ACD) by examining the connections between individual susceptibility, patient characteristics, and dermatitis expressions. The study employs both classic statistical techniques and advanced machine learning methods to analyze data from patch tests. By identifying relationships among various clinical characteristics, the research seeks to enhance understanding of ACD and improve diagnostic accuracy.
Who should consider this trial
Good fit: Ideal candidates for this study are adults diagnosed with dermatitis who have tested positive on a patch test for allergens.
Not a fit: Patients with chronic use of anti-inflammatory treatments or other conditions that may interfere with patch test results may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to more accurate diagnoses and personalized treatment strategies for patients with allergic contact dermatitis.
How similar studies have performed: While the use of machine learning in dermatological studies is emerging, this specific approach to investigating contact sensitization is relatively novel and has not been extensively tested in prior studies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: - Eligible patients were adults diagnosed with dermatitis who had a positive patch test result on the chemical panel of Baseline Series of Allergens. Exclusion Criteria: - Although there is no consensus for the definitive exclusion criteria from a patch testing, most studies agree that the chronic use of anti-inflammatory treatments, corticosteroids, and cyclosporine, high UV exposure and other chronic dermatoses are factors that might produce false- positive or false- negative results and thus should be avoided.
Where this trial is running
Athens, Attica
- Georgia Gogkla — Athens, Attica, Greece (RECRUITING)
Study contacts
- Study coordinator: Aikaterini Kyritsi
- Email: akyrits@pharm.uoa.gr
- Phone: +30 2107274027
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Allergic Contact Dermatitis, Contact Sensitization, Patch Test, Machine Learning