Investigating clopidogrel response in patients with cerebral aneurysms
Clopidogrel Hyper-Responsiveness: Incidence and Associated Outcomes in Patients With Cerebral Aneurysms
This study looks at how well clopidogrel works for people with cerebral aneurysms and what effects it has on their health.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 208 (estimated) |
| Ages | 18 Years to 85 Years |
| Sex | All |
| Sponsor | Methodist Health System Academic / other |
| Locations | 1 site (Dallas, Texas) |
| Trial ID | NCT05945563 on ClinicalTrials.gov |
What this trial studies
This observational registry study aims to assess the incidence of clopidogrel hyper-responsiveness and its associated outcomes in patients diagnosed with cerebral aneurysms at Methodist Dallas Medical Center. The study will collect perioperative and short-term clinical data from electronic medical records, including demographics, patient characteristics, and pre-operative medical history. The data will be systematically documented to provide insights into the effects of clopidogrel treatment in this patient population.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 18 years or older who have been diagnosed with cerebral aneurysms and are undergoing pre-intervention treatment with clopidogrel.
Not a fit: Patients who do not meet the inclusion criteria, such as those under 18 or without a diagnosis of cerebral aneurysms, may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance understanding of clopidogrel's effectiveness and safety in patients with cerebral aneurysms, potentially leading to improved treatment strategies.
How similar studies have performed: While there may be studies on clopidogrel's effects in other conditions, this specific investigation into clopidogrel hyper-responsiveness in cerebral aneurysm patients is novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: Age 18 years or older Diagnosed with cerebral aneurysms (i.e. ICD-10 i67.1) Pre-intervention treatment with clopidogrel Exclusion Criteria: * Does not meet inclusion criteria specified in 3.1
Where this trial is running
Dallas, Texas
- Methodist Dallas Medical Center — Dallas, Texas, United States (Recruiting)
Study contacts
- Study coordinator: Colette N Ndjom, MS
- Email: MHSIRB@mhd.com
- Phone: 214-947-1280
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.