Investigating causes of fever in Guinea
Official title: Multidisciplinary Surveillance and Investigation of Febrile Illness in Guinea
Run by Centre National de Formation et de Recherche en Sante Rurale · NCT06122259 · Data updated 2026-11-12
This study is trying to find out what causes fevers that aren't due to malaria in people in Guinea to help doctors diagnose and treat them better.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 2 Months and up |
| Sex | All |
| Enrollment | 2500 (estimated) |
| Sponsor | Centre National de Formation et de Recherche en Sante Rurale Government |
| Locations | 1 site (Maférinya, Forécariah) |
| Status | Recruiting |
| Started | March 27, 2023 |
| Main results expected | December 31, 2026 |
| Study ends | December 31, 2026 |
| Registry record updated | November 8, 2023 |
| Trial ID | NCT06122259 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include individuals aged 2 months and older who present with documented fever or have reported fever within the last 24 hours.
✕Probably not a fit
Patients with a history of hospitalization for more than 48 hours within the last 14 days may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to document the underlying causes of community-acquired febrile illness, particularly non-malarial fever, in Guinea. It involves a prospective multi-centric cohort of febrile patients presenting at emergency and outpatient departments across selected health centers and hospitals in four distinct health districts. The study seeks to improve diagnostic capacity and timely recognition of outbreaks, which are currently hindered by inadequate data and resources. Participants will be followed for 21 days to gather comprehensive clinical information.
Why it matters
Potential benefit: If successful, this study could enhance the understanding and management of febrile illnesses in Guinea, leading to better treatment protocols and improved patient outcomes.
How similar studies have gone: While there may be limited data on similar studies in Guinea, the approach of documenting febrile illnesses has shown promise in other regions with similar healthcare challenges.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age ≥2 months old * Documented fever (axillary temperature \>37.5°C) at presentation or fever reported within the prior 24 hours * Availability for follow-up for 21 days * Willingness and ability of the patient or culturally acceptable representative to give informed consent for participation in the study Exclusion Criteria: * History of hospitalization (for \> 48 hours within the last 14 days) at any health facility
Where it's running
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Centre National de Formation et de Recherche en Santé Rurale
Maférinya, Forécariah, Guinea Recruiting
Study contacts
- Study coordinator: Karifa Kourouma, MD, MSc
- Email: KKourouma@maferinyah.org
- Phone: +224-628-765-320
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Causes of unexplained fevers in Nepal (DEFINe)
This project will test whether adding cultures and ELISA blood tests can find the causes of fever and reduce unnecessary antibiotic use in adults admitted with 3–21 day unexplained fevers in Nepal.
-
Understanding vaccination attitudes during mild fever
This study looks at how healthcare workers and the general public feel about getting vaccinated when they have a mild fever to see what might help or stop them from getting vaccinated in those situations.
-
Rapid suPAR blood test to help triage febrile young children
This study will test whether adding a quick suPAR point-of-care blood test to standard IMCI triage helps health workers better spot children aged 2–59 months with fever who need admission or referral.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.