Investigating causes of fever in Guinea
Multidisciplinary Surveillance and Investigation of Febrile Illness in Guinea
Centre National de Formation et de Recherche en Sante Rurale · NCT06122259
This study is trying to find out what causes fevers that aren't due to malaria in people in Guinea to help doctors diagnose and treat them better.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 2500 (estimated) |
| Ages | 2 Months and up |
| Sex | All |
| Sponsor | Centre National de Formation et de Recherche en Sante Rurale (other gov) |
| Locations | 1 site (Maférinya, Forécariah) |
| Trial ID | NCT06122259 on ClinicalTrials.gov |
What this trial studies
This observational study aims to document the underlying causes of community-acquired febrile illness, particularly non-malarial fever, in Guinea. It involves a prospective multi-centric cohort of febrile patients presenting at emergency and outpatient departments across selected health centers and hospitals in four distinct health districts. The study seeks to improve diagnostic capacity and timely recognition of outbreaks, which are currently hindered by inadequate data and resources. Participants will be followed for 21 days to gather comprehensive clinical information.
Who should consider this trial
Good fit: Ideal candidates include individuals aged 2 months and older who present with documented fever or have reported fever within the last 24 hours.
Not a fit: Patients with a history of hospitalization for more than 48 hours within the last 14 days may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance the understanding and management of febrile illnesses in Guinea, leading to better treatment protocols and improved patient outcomes.
How similar studies have performed: While there may be limited data on similar studies in Guinea, the approach of documenting febrile illnesses has shown promise in other regions with similar healthcare challenges.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age ≥2 months old * Documented fever (axillary temperature \>37.5°C) at presentation or fever reported within the prior 24 hours * Availability for follow-up for 21 days * Willingness and ability of the patient or culturally acceptable representative to give informed consent for participation in the study Exclusion Criteria: * History of hospitalization (for \> 48 hours within the last 14 days) at any health facility
Where this trial is running
Maférinya, Forécariah
- Centre National de Formation et de Recherche en Santé Rurale — Maférinya, Forécariah, Guinea (RECRUITING)
Study contacts
- Study coordinator: Karifa Kourouma, MD, MSc
- Email: KKourouma@maferinyah.org
- Phone: +224-628-765-320
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Febrile Illness