Investigating cardiovascular responses in young athletes
Influence of Vigorous Physical Activity and Metabolic Parameters on Structure and Function of the Cardiovascular System in Young Athletes - the MuCAYAplus - Study (Munich Cardiovascular Adaptation in Young Athletes Study)
This study looks at how the hearts and blood vessels of young athletes change as they train over three years to see how different training loads affect their cardiovascular health.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 250 (estimated) |
| Ages | 7 Years to 18 Years |
| Sex | All |
| Sponsor | Technical University of Munich Academic / other |
| Locations | 1 site (München, Bavaria) |
| Trial ID | NCT06259617 on ClinicalTrials.gov |
What this trial studies
This observational study aims to explore how the cardiovascular system of young athletes adapts to different training loads over a three-year period. It will assess structural and functional changes in the heart and blood vessels, alongside biochemical and metabolic measures, to understand the impact of training frequency and intensity on cardiovascular health. Participants will undergo annual sports medical examinations to monitor these changes and their relationship with athletic performance.
Who should consider this trial
Good fit: Ideal candidates are young athletes aged 7 to 17 who engage in regular training and competition in their primary sport.
Not a fit: Patients who do not participate in competitive sports or those with acute infections, orthopedic injuries, or chronic diseases may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide insights into optimizing training regimens for young athletes to enhance cardiovascular health and performance.
How similar studies have performed: While there have been studies on adult athletes, this specific focus on young athletes' cardiovascular adaptation is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Participants aged ≥7 and \<18 years, presenting for sports medical examination and meeting the criteria mentioned for a period of 3 years * Athletes participating in competitions, engaging in regular training in a primary sport, being members of a club or association, and training ≥3 hours per week * The last intensive training must have occurred 12 hours ago to ensure sufficient recovery * No acute infection, confirmed by a medical examination on the day of testing * No orthopedic injury, confirmed by a medical examination on the day of testing * No chronic disease, confirmed by a medical examination on the day of testing * Clearance for cardiopulmonary stress testing after a medical examination on the day of testing * Annual participation (1 time per year) in the sports medical examination for 3 years * Maintaining regular training, training duration ≥3 hours per week, and participation in competitions Exclusion Criteria: * Presence of an acute infection, acute orthopedic injury, or chronic disease * Missing consent from the participant and/or legal guardian
Where this trial is running
München, Bavaria
- Sportmedizinische Ambulanz für Kinder und Jugendliche — München, Bavaria, Germany (Recruiting)
Study contacts
- Principal investigator: Thorsten Schulz, Dr. — Technical University of Munich
- Study coordinator: Tobias Engl, Dipl. Sportwiss. Univ.
- Email: tobias.engl@tum.de
- Phone: +49 89 289 24598
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.