Investigating brain injury markers in divers with decompression sickness

Neuroskademarkörer Vid Dykarsjuka

Observational Sahlgrenska University Hospital · NCT03192956

This study is testing if certain fluid markers in the blood can show brain injury in divers who have decompression sickness and how these markers relate to their diving experiences and the severity of their condition.

Quick facts

Study typeObservational
Enrollment40 (estimated)
Ages18 Years and up
SexAll
SponsorSahlgrenska University Hospital Academic / other
Locations1 site (Gothenburg)
Trial IDNCT03192956 on ClinicalTrials.gov

What this trial studies

This observational study aims to assess the presence of fluid markers indicating central nervous system (CNS) injury in individuals suffering from decompression sickness (DCS). It will evaluate the correlation between these markers and both the diving profile and severity of DCS, as well as the relationship between inflammatory markers and DCS. Participants will be recruited by attending physicians at the Hyperbaric unit, and blood samples will be analyzed to identify potential indicators of CNS injury and inflammation. The study seeks to enhance understanding of the pathophysiology of DCS and its neurological implications.

Who should consider this trial

Good fit: Ideal candidates for this study are individuals who are currently experiencing symptoms of decompression sickness.

Not a fit: Patients who do not have decompression sickness or those who are not divers may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved diagnostic and treatment strategies for divers experiencing decompression sickness.

How similar studies have performed: While studies have shown the presence of CNS injury markers in athletes, this specific approach in divers with DCS is novel and has not been extensively tested.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Presence of decompression sickness
* Signed informed consent

Exclusion Criteria:

* As this is a highly selected population there is no exclusion criteria

Where this trial is running

Gothenburg

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Decompression SicknessHyperbaricDecompression sicknessDecompression injuryInflammationCentral nervous injuryHybervaric oxygen therapy
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.