Investigating brain factors that affect fibromyalgia pain treatment

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to explore the biological, psychological, and social factors that influence the effectiveness of pain treatments in individuals suffering from fibromyalgia. By identifying specific biomarkers, the researchers hope to develop tailored treatment strategies that can improve patient outcomes. Participants will undergo assessments to evaluate their chronic pain and related characteristics, with the goal of enhancing the understanding of how these factors interact with pain management. The study will utilize placebos as part of its methodology to assess treatment responses.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Chronic pain participant inclusion criteria:

  1. 18-75 years of age
  2. Right-handed
  3. Meet the classification criteria of chronic low back pain (having low back pain for more than 6 months).
  4. At least 4/10 clinical pain on the Brief Pain Inventory Scale on average during the two weeks prior to enrollment
  5. Comfortable completing (reading and writing) questionnaires and tasks with English language instructions

Healthy participant inclusion criteria:

1. 18 - 75 years of age
2. Right-handed
3. Comfortable completing (reading and writing) questionnaires and tasks with English language instructions

Exclusion Criteria:

Chronic pain participant exclusion criteria:

1. History of cardiac, respiratory, or nervous system disease that may interfere with participation in the study or cause heightened potential for adverse outcome. For example: asthma or claustrophobia
2. Presence of any contraindications to MRI scanning. For example:

cardiac pacemaker, metal implants, fear of closed spaces, pregnancy

Healthy participant exclusion criteria:

1. Acute or chronic pain
2. History of cardiac, respiratory, or nervous system disease that, in the investigator's judgment and by asking the participant about their comfort level and ability, precludes participation in the study because of a heightened potential for adverse outcome. For example: asthma or claustrophobia
3. Presence of any contraindications to MRI scanning. For example:

cardiac pacemaker, metal implants, fear of closed spaces, pregnancy.

Where it's running

• Nova Scotia Health Authority
  Halifax, Nova Scotia, Canada Recruiting

Study contacts

• Study coordinator: Javeria A Hashmi, PhD
• Email: javeria.hashmi@dal.ca
• Phone: 902-473-4603

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.