Investigating brain changes in hereditary ataxia patients
Neuroimaging Changes in Hereditary Ataxia
Second Affiliated Hospital, School of Medicine, Zhejiang University · NCT05160883
This study is trying to see how hereditary ataxia, especially in people with Spinocerebellar Ataxia type 3, affects the brain in the early stages of the condition.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 500 (estimated) |
| Ages | 18 Years to 65 Years |
| Sex | All |
| Sponsor | Second Affiliated Hospital, School of Medicine, Zhejiang University (other) |
| Locations | 1 site (Hangzhou, Zhejiang) |
| Trial ID | NCT05160883 on ClinicalTrials.gov |
What this trial studies
This observational study aims to explore neuroimaging changes in patients diagnosed with hereditary ataxia, with a particular focus on those with Spinocerebellar Ataxia type 3 (SCA3) who are in the preclinical or mild stages of the condition. By utilizing advanced imaging techniques, the study seeks to identify specific brain alterations associated with the disease. The findings could enhance understanding of the progression of hereditary ataxia and inform future therapeutic strategies.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals who have been genetically diagnosed with Spinocerebellar Ataxia.
Not a fit: Patients who do not wish to participate in follow-up assessments will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide insights into the early neuroimaging markers of hereditary ataxia, potentially leading to earlier diagnosis and intervention.
How similar studies have performed: While there have been studies on neuroimaging in ataxia, this specific focus on preclinical and mild stages of SCA3 is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * genetically diagnosed as Spinocerebellar ataxia Exclusion Criteria: * deny to follow-up
Where this trial is running
Hangzhou, Zhejiang
- Second Affiliated Hospital,Zhejiang University School of Medicine — Hangzhou, Zhejiang, China (RECRUITING)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Hereditary Ataxia