Investigating brain and kidney changes in aging using MRI
Technical Development of Multi-Parametric Renocerebral MRI
University of Minnesota · NCT02831335
This study is trying to see how aging affects the brain and kidneys and how these changes relate to thinking skills in healthy adults.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 120 (estimated) |
| Ages | 21 Years to 80 Years |
| Sex | All |
| Sponsor | University of Minnesota (other) |
| Locations | 1 site (Minneapolis, Minnesota) |
| Trial ID | NCT02831335 on ClinicalTrials.gov |
What this trial studies
This study aims to explore the relationships between age-related changes in the brain and kidneys, as well as cognitive performance in healthy adults. It employs various anatomic and functional MRI techniques alongside cognitive assessments to gather comprehensive data. By analyzing these associations, the study seeks to enhance understanding of how aging affects brain and kidney function and cognitive abilities.
Who should consider this trial
Good fit: Ideal candidates for this study are healthy adults who are English-speaking and have no significant sensory impairments.
Not a fit: Patients with a history of cardiovascular diseases, chronic obstructive pulmonary disease, renal diseases, cognitive disorders, or those on certain medications may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide insights into the aging process and help develop strategies to maintain cognitive health in older adults.
How similar studies have performed: While there have been studies investigating aging and cognitive performance, this specific multi-parametric MRI approach is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. English-speaking as primary language 2. No hearing loss or uncorrected vision Exclusion Criteria: 1. Lacking capacity to consent 2. Having known history of cardiovascular diseases (e.g., clinical stroke) 3. Having acute and chronic obstructive pulmonary disease 4. Having known history of renal diseases (e.g., acute kidney injury) 5. Having known history of cognitive disorder or psychiatric illness 6. Having known history of chemical dependence (e.g., alcohol and narcotics) 7. Being treated with stimulant medications, anticonvulsants, antihypertensives or ß-adrenergic blockers
Where this trial is running
Minneapolis, Minnesota
- Center for Magnetic Resonance Research — Minneapolis, Minnesota, United States (RECRUITING)
Study contacts
- Principal investigator: Xiufeng Li, Ph.D. — University of Minnesota
- Study coordinator: Xiufeng Li, Ph.D.
- Email: lixx1607@umn.edu
- Phone: 6126258258
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Aging