Investigating brain and eye markers related to facial expression recognition in autism
Brain and Eye Markers of Facial Expression Recognition and Disorders Associated with Autistic Symptoms
This study is trying to see how attention and memory help people with autism and certain genetic conditions recognize emotions in faces compared to those without these conditions.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 120 (estimated) |
| Ages | 7 Years to 50 Years |
| Sex | All |
| Sponsor | Centre Hospitalier Universitaire Dijon Academic / other |
| Locations | 1 site (Dijon) |
| Trial ID | NCT05635812 on ClinicalTrials.gov |
What this trial studies
This observational study aims to explore how attention and memory processes affect emotion recognition, particularly in individuals with autism spectrum disorder (ASD) and those with specific genetic syndromes. It will assess the use of compensatory strategies for recognizing emotions and their relationship with autistic and psychotic symptoms. A total of 120 participants will be included, consisting of individuals with ASD, those with genetic syndromes, and typically developing individuals matched by age and gender. The study will utilize neuropsychological assessments, EEG, and oculometry to gather data.
Who should consider this trial
Good fit: Ideal candidates include individuals aged 7 to 50 diagnosed with ASD or specific genetic syndromes, as well as typically developing individuals matched by age and gender.
Not a fit: Patients with recent addictions, uncorrected visual acuity disorders, or neurological disorders may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance understanding of emotion recognition difficulties in autism, leading to better-targeted interventions.
How similar studies have performed: While similar studies have explored emotion recognition in autism, this specific approach focusing on brain and eye markers is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Person, and if necessary his or her legal representative, who has given his or her non-objection * Person whose mother tongue is French. * Person aged between 7 and 50 years old. * Person diagnosed with ASD according to DSM-5 criteria, person with a genetic syndrome diagnosed by FISH or CGH array (22q11 deletion), person with typical development matched in age and gender. * Psychotropic treatment unchanged for one month and stable symptomatology. Exclusion Criteria: * Recent addiction according to DSM-5 criteria, excluding tobacco. * Pregnant women. * Uncorrected visual acuity disorder. * Use of somatic or psychic medication that may alter brain/psychic functioning (e.g. corticosteroids). * Neurological disorder of vascular/infectious or neurodegenerative origin.
Where this trial is running
Dijon
- Chu Dijon Bourogne — Dijon, France (Recruiting)
Study contacts
- Study coordinator: Jean-Michel PINOIT
- Email: jean-michel.pinoit@chu-dijon.fr
- Phone: 03 80 29 34 60
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.