Investigating brain activity patterns in movement disorders

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This research aims to explore the oscillatory activity in the cortico-subcortical network during normal and pathological movements in patients with Parkinson's disease and drug-resistant epilepsy. By utilizing high-resolution electroencephalogram (EEG) and stereo-electro-encephalography (SEEG), the study will collect local field potentials while participants perform a simple motor task. The goal is to understand the relationship between the characteristics of these oscillations and movement patterns, which could provide insights into the underlying mechanisms of these disorders.

Why it matters

Who can join: the full rules

Inclusion criteria :

* Male or Female
* Between 18 and 75 years of age
* With Parkinson's disease and already operated with implantation of electrodes in the Subthalamic nucleus connected to a PERCEPT (TM) device.
* Giving free, informed, written consent signed by the participant and the investigator Or
* With drug-resistant epilepsy and benefiting from a phase II pre-surgical assessment with intracerebral electrophysiological exploration by stereo-EEG
* With at least one electrode exploring the basal ganglia or the thalamus.
* Able to perform the simple motor task
* Affiliated or beneficiary of a social security scheme;
* Giving free, informed, written consent signed by the participant and the investigator

Exclusion criteria:

* Be incapable of giving consent personally
* Be subject to a legal protection measure or be placed under judicial protection;
* Being pregnant or breastfeeding
* Present a serious and/or decompensated somatic or psychiatric illness

Where it's running

• CHU de Bordeaux
  Bordeaux, France Recruiting

Study contacts

• Principal investigator: Jérôme AUPY, Docteur — University Hospital, Bordeaux
• Study coordinator: Jérôme AUPY, Docteur
• Email: jerome.aupy@u-bordeaux.fr
• Phone: 05 56 71 43 33

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.