Investigating brain activity during vibration-induced movement illusions in healthy and stroke patients
Vibration-induced Movement Illusion Causes Cerebral Haemodynamic Changes: A fNIRS Study.
This study is testing how the brain reacts to vibrations that create the feeling of movement in both healthy people and those who have had a stroke.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 90 (estimated) |
| Ages | 18 Years to 85 Years |
| Sex | All |
| Sponsor | Centre Hospitalier Régional d'Orléans Academic / other |
| Locations | 1 site (Orleans) |
| Trial ID | NCT06218563 on ClinicalTrials.gov |
What this trial studies
This study aims to explore how the brain responds to vibration-induced illusions of movement in both healthy individuals and those who have experienced a stroke. Participants will undergo a series of vibration conditions while their cerebral activation is monitored using functional near-infrared spectroscopy (fNIRS). The study will compare the subjective sensations of movement and brain activity between healthy participants and stroke patients, focusing on the effects of vibration on the perception of limb movement. The research seeks to enhance understanding of proprioception and its neural correlates in different populations.
Who should consider this trial
Good fit: Ideal candidates include healthy individuals aged 18-85 who are right-handed and stroke patients in the acute phase of recovery.
Not a fit: Patients with severe aphasia or those unable to perceive vibrations on the affected side may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve rehabilitation strategies for stroke patients by enhancing our understanding of proprioceptive feedback mechanisms.
How similar studies have performed: While the use of fNIRS in studying proprioception is innovative, similar studies have shown promise in understanding brain activation patterns during sensory stimulation.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * 18-85 years old * Able to sign a consent form * Sufficient command of the French language to understand instructions * Affiliated to a social security scheme Healthy participants: * Right handed * No neurological disease or motor deficit Stroke participants: * Stroke volunteers in acute phase (before day 14 post-stroke) * Not aphasic * Able to maintain sitting position without difficulty * Deficit moteur * Able to sign a consent form Exclusion Criteria: * Person under tutorship or curatorship * Known allergy to of the fNIRS cap components: neoprene * No vibrations feeling on the deficient side * Vigilance-modifying drugs (high-dose psychotropics, antispastic drugs)
Where this trial is running
Orleans
- CHU d'ORLEANS — Orleans, France (Recruiting)
Study contacts
- Principal investigator: Canan OZSANCAK, Dr — CHU d'Orléans
- Study coordinator: Elodie POUGOUE
- Email: elodie.pougoue-touko@chu-orleans.fr
- Phone: +33238744086
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.