Investigating brain activity and walking ability in Parkinson's disease
Brain Activity, Cognitive Function, and Walking Ability in People With Parkinson's Disease
This study looks at how brain activity linked to thinking skills affects walking in people with Parkinson's disease compared to healthy older adults.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 70 (estimated) |
| Ages | 40 Years to 80 Years |
| Sex | All |
| Sponsor | National Yang Ming Chiao Tung University Academic / other |
| Locations | 2 sites (Taipei and 1 other locations) |
| Trial ID | NCT06588920 on ClinicalTrials.gov |
What this trial studies
This observational study examines how brain activity related to executive functions affects walking performance in individuals with Parkinson's disease and healthy older adults. It focuses on the relationship between inhibitory control, cognitive function, and gait stability. Participants will undergo assessments of their cognitive abilities and walking performance while their brain activity is monitored using electroencephalography. The goal is to better understand the impact of cognitive functions on gait disturbances in Parkinson's disease.
Who should consider this trial
Good fit: Ideal candidates include individuals diagnosed with idiopathic Parkinson's disease who can walk independently and have stable medication.
Not a fit: Patients with other neurological, musculoskeletal, or cardiopulmonary disorders may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved strategies for managing gait disturbances in patients with Parkinson's disease.
How similar studies have performed: While the specific relationship between brain activity and dual-task walking in Parkinson's disease is not well established, similar studies have explored cognitive function impacts on gait, suggesting potential for meaningful insights.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Diagnoses of idiopathic Parkinson disease * Stable dopaminergic medicine ≥ 2 weeks * Able to walk 10 meters without aid * Mini-Mental Status Examination ≥ 24 points * No uncorrected visual or auditory disorders * Education at least junior high school * No other disease may affect balance Exclusion Criteria: * Other medical diagnoses of neurological, musculoskeletal, or cardiopulmonary disorders * History of brain surgery (e.g. deep brain stimulation)
Where this trial is running
Taipei and 1 other locations
- National Yang Ming Chiao Tung University — Taipei, Taiwan (Recruiting)
- National Yang Ming Chiao Tung University — Taipei, Taiwan (Recruiting)
Study contacts
- Study coordinator: Yea-Ru Yang, PhD
- Email: yryang@nycu.edu.tw
- Phone: +886228267279
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.