Clinical trial Recruiting at 2 sites Observational Ages 40 to 80

Investigating brain activity and walking ability in Parkinson's disease

Official title: Brain Activity, Cognitive Function, and Walking Ability in People With Parkinson's Disease

Run by National Yang Ming Chiao Tung University · NCT06588920 · Data updated 2026-11-12

This study looks at how brain activity linked to thinking skills affects walking in people with Parkinson's disease compared to healthy older adults.

Quick facts

Study typeObservational
Ages40 Years to 80 Years
SexAll
Enrollment70 (estimated)
SponsorNational Yang Ming Chiao Tung University
Academic / other
Locations2 sites (Taipei and 1 other locations)
StatusRecruiting
StartedOctober 9, 2024
Main results expectedAugust 31, 2027
Study endsAugust 31, 2027
Registry record updatedMarch 24, 2026
Trial IDNCT06588920 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include individuals diagnosed with idiopathic Parkinson's disease who can walk independently and have stable medication.

Probably not a fit

Patients with other neurological, musculoskeletal, or cardiopulmonary disorders may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study examines how brain activity related to executive functions affects walking performance in individuals with Parkinson's disease and healthy older adults. It focuses on the relationship between inhibitory control, cognitive function, and gait stability. Participants will undergo assessments of their cognitive abilities and walking performance while their brain activity is monitored using electroencephalography. The goal is to better understand the impact of cognitive functions on gait disturbances in Parkinson's disease.

Why it matters

Potential benefit: If successful, this study could lead to improved strategies for managing gait disturbances in patients with Parkinson's disease.

How similar studies have gone: While the specific relationship between brain activity and dual-task walking in Parkinson's disease is not well established, similar studies have explored cognitive function impacts on gait, suggesting potential for meaningful insights.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Diagnoses of idiopathic Parkinson disease
* Stable dopaminergic medicine ≥ 2 weeks
* Able to walk 10 meters without aid
* Mini-Mental Status Examination ≥ 24 points
* No uncorrected visual or auditory disorders
* Education at least junior high school
* No other disease may affect balance

Exclusion Criteria:

* Other medical diagnoses of neurological, musculoskeletal, or cardiopulmonary disorders
* History of brain surgery (e.g. deep brain stimulation)

Where it's running

  • National Yang Ming Chiao Tung University
    Taipei, Taiwan
    Recruiting
  • National Yang Ming Chiao Tung University
    Taipei, Taiwan
    Recruiting

Study contacts

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.