Investigating brain activity and walking ability in Parkinson's disease
Official title: Brain Activity, Cognitive Function, and Walking Ability in People With Parkinson's Disease
Run by National Yang Ming Chiao Tung University · NCT06588920 · Data updated 2026-11-12
This study looks at how brain activity linked to thinking skills affects walking in people with Parkinson's disease compared to healthy older adults.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 40 Years to 80 Years |
| Sex | All |
| Enrollment | 70 (estimated) |
| Sponsor | National Yang Ming Chiao Tung University Academic / other |
| Locations | 2 sites (Taipei and 1 other locations) |
| Status | Recruiting |
| Started | October 9, 2024 |
| Main results expected | August 31, 2027 |
| Study ends | August 31, 2027 |
| Registry record updated | March 24, 2026 |
| Trial ID | NCT06588920 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include individuals diagnosed with idiopathic Parkinson's disease who can walk independently and have stable medication.
✕Probably not a fit
Patients with other neurological, musculoskeletal, or cardiopulmonary disorders may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study examines how brain activity related to executive functions affects walking performance in individuals with Parkinson's disease and healthy older adults. It focuses on the relationship between inhibitory control, cognitive function, and gait stability. Participants will undergo assessments of their cognitive abilities and walking performance while their brain activity is monitored using electroencephalography. The goal is to better understand the impact of cognitive functions on gait disturbances in Parkinson's disease.
Why it matters
Potential benefit: If successful, this study could lead to improved strategies for managing gait disturbances in patients with Parkinson's disease.
How similar studies have gone: While the specific relationship between brain activity and dual-task walking in Parkinson's disease is not well established, similar studies have explored cognitive function impacts on gait, suggesting potential for meaningful insights.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Diagnoses of idiopathic Parkinson disease * Stable dopaminergic medicine ≥ 2 weeks * Able to walk 10 meters without aid * Mini-Mental Status Examination ≥ 24 points * No uncorrected visual or auditory disorders * Education at least junior high school * No other disease may affect balance Exclusion Criteria: * Other medical diagnoses of neurological, musculoskeletal, or cardiopulmonary disorders * History of brain surgery (e.g. deep brain stimulation)
Where it's running
-
National Yang Ming Chiao Tung University
Taipei, Taiwan Recruiting -
National Yang Ming Chiao Tung University
Taipei, Taiwan Recruiting
Study contacts
- Study coordinator: Yea-Ru Yang, PhD
- Email: yryang@nycu.edu.tw
- Phone: +886228267279
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
One-day exercise test to see how brain and body react in epilepsy, cognitive disorders, Parkinson's, dementia, and related conditions
A one-day study tests how an acute bout of exercise changes brain function and bodily signals in people with certain neurological conditions compared with healthy individuals.
-
Tributyrin for PSP: a virtual, early-phase study
This study tests whether tributyrin is safe and tolerable in people with Progressive Supranuclear Palsy who are 45 or older, using virtual visits.
-
A look at why Lewy body conditions cause visual hallucinations
This study tests brain‑imaging in people with Lewy body diseases who do or don’t experience visual hallucinations, and in healthy volunteers, to see how brain networks might create these images.
-
How physical activity might help people with Parkinson’s disease who have DBS-STN implants
This study tests whether adding regular physical activity can help people with Parkinson’s who have DBS-STN stimulation by trying a structured physiotherapy approach alongside standard care.
-
Can hippotherapy improve mobility, gait, balance, and quality of life in people with Parkinson's disease?
This pilot trial tests whether adding horse-assisted therapy to standard rehab helps mobility, gait, balance, and perceived health in adults with Parkinson's disease.
-
Gut methane and Parkinson's: measuring if a probiotic helps people with Parkinson's, REM sleep behavior disorder, or cognitive concerns
This study tests whether a probiotic containing Limosilactobacillus reuteri can help people with Parkinson's disease, those at high risk for PD, and related cognitive issues by potentially improving gut methane levels and overall symptoms.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.