Investigating blood microparticles in acute carbon monoxide poisoning
Microparticles Blood Level in Acute Carbon Monoxide Poisoning
This study looks at the levels of tiny particles in the blood of people with acute carbon monoxide poisoning to see how they change with treatment and how they relate to the severity of the poisoning.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 108 (estimated) |
| Ages | 18 Years to 99 Years |
| Sex | All |
| Sponsor | Azienda Ospedaliero Universitaria Maggiore della Carita Academic / other |
| Locations | 1 site (Novara) |
| Trial ID | NCT05591300 on ClinicalTrials.gov |
What this trial studies
This observational study aims to explore the levels of circulating microparticles in patients suffering from acute carbon monoxide (CO) poisoning compared to healthy controls. Blood samples will be collected from patients before and after hyperbaric oxygen treatment to assess any changes in microparticle levels. The study will also investigate the relationship between the severity of CO intoxication and microparticle levels, as well as potential risk factors for delayed neurological syndrome. The findings could enhance understanding of CO toxicity and its long-term effects.
Who should consider this trial
Good fit: Ideal candidates for this study are adults over 18 years old who have experienced acute carbon monoxide poisoning and require hyperbaric oxygen treatment.
Not a fit: Patients who do not consent to participate in the study will not benefit from its findings.
Why it matters
Potential benefit: If successful, this study could lead to improved diagnostic and therapeutic strategies for patients suffering from carbon monoxide poisoning.
How similar studies have performed: While studies have shown increased microparticle levels in animal models of CO intoxication, this specific approach in humans is novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age \> 18 years * Acute carbon monoxide poisoning * Need for treatment with hyperbaric oxygen Exclusion Criteria: * Patient reject to consent
Where this trial is running
Novara
- AOU Maggiore della Carità — Novara, Italy (Recruiting)
Study contacts
- Principal investigator: Rosanna Vaschetto, MD, PhD — University of Eastern Piedmont
- Study coordinator: Rosanna Vaschetto
- Email: rosanna.vaschetto@med.uniupo.it
- Phone: +39 3342724811
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.