Investigating blood microparticles in acute carbon monoxide poisoning
Official title: Microparticles Blood Level in Acute Carbon Monoxide Poisoning
Run by Azienda Ospedaliero Universitaria Maggiore della Carita · NCT05591300 · Data updated 2026-11-12
This study looks at the levels of tiny particles in the blood of people with acute carbon monoxide poisoning to see how they change with treatment and how they relate to the severity of the poisoning.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 99 Years |
| Sex | All |
| Enrollment | 108 (estimated) |
| Sponsor | Azienda Ospedaliero Universitaria Maggiore della Carita Academic / other |
| Locations | 1 site (Novara) |
| Status | Recruiting |
| Started | November 15, 2022 |
| Main results expected | April 2025 |
| Study ends | November 2025 |
| Registry record updated | November 14, 2024 |
| Trial ID | NCT05591300 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults over 18 years old who have experienced acute carbon monoxide poisoning and require hyperbaric oxygen treatment.
✕Probably not a fit
Patients who do not consent to participate in the study will not benefit from its findings.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to explore the levels of circulating microparticles in patients suffering from acute carbon monoxide (CO) poisoning compared to healthy controls. Blood samples will be collected from patients before and after hyperbaric oxygen treatment to assess any changes in microparticle levels. The study will also investigate the relationship between the severity of CO intoxication and microparticle levels, as well as potential risk factors for delayed neurological syndrome. The findings could enhance understanding of CO toxicity and its long-term effects.
Why it matters
Potential benefit: If successful, this study could lead to improved diagnostic and therapeutic strategies for patients suffering from carbon monoxide poisoning.
How similar studies have gone: While studies have shown increased microparticle levels in animal models of CO intoxication, this specific approach in humans is novel and has not been extensively tested.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age \> 18 years * Acute carbon monoxide poisoning * Need for treatment with hyperbaric oxygen Exclusion Criteria: * Patient reject to consent
Where it's running
-
AOU Maggiore della Carità
Novara, Italy Recruiting
Study contacts
- Principal investigator: Rosanna Vaschetto, MD, PhD — University of Eastern Piedmont
- Study coordinator: Rosanna Vaschetto
- Email: rosanna.vaschetto@med.uniupo.it
- Phone: +39 3342724811
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.