Clinical trial Recruiting at 1 site Observational Ages 18 to 99

Investigating blood microparticles in acute carbon monoxide poisoning

Official title: Microparticles Blood Level in Acute Carbon Monoxide Poisoning

Run by Azienda Ospedaliero Universitaria Maggiore della Carita · NCT05591300 · Data updated 2026-11-12

This study looks at the levels of tiny particles in the blood of people with acute carbon monoxide poisoning to see how they change with treatment and how they relate to the severity of the poisoning.

Quick facts

Study typeObservational
Ages18 Years to 99 Years
SexAll
Enrollment108 (estimated)
SponsorAzienda Ospedaliero Universitaria Maggiore della Carita
Academic / other
Locations1 site (Novara)
StatusRecruiting
StartedNovember 15, 2022
Main results expectedApril 2025
Study endsNovember 2025
Registry record updatedNovember 14, 2024
Trial IDNCT05591300 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adults over 18 years old who have experienced acute carbon monoxide poisoning and require hyperbaric oxygen treatment.

Probably not a fit

Patients who do not consent to participate in the study will not benefit from its findings.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to explore the levels of circulating microparticles in patients suffering from acute carbon monoxide (CO) poisoning compared to healthy controls. Blood samples will be collected from patients before and after hyperbaric oxygen treatment to assess any changes in microparticle levels. The study will also investigate the relationship between the severity of CO intoxication and microparticle levels, as well as potential risk factors for delayed neurological syndrome. The findings could enhance understanding of CO toxicity and its long-term effects.

Why it matters

Potential benefit: If successful, this study could lead to improved diagnostic and therapeutic strategies for patients suffering from carbon monoxide poisoning.

How similar studies have gone: While studies have shown increased microparticle levels in animal models of CO intoxication, this specific approach in humans is novel and has not been extensively tested.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age \> 18 years
* Acute carbon monoxide poisoning
* Need for treatment with hyperbaric oxygen

Exclusion Criteria:

* Patient reject to consent

Where it's running

  • AOU Maggiore della Carità
    Novara, Italy
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.