Investigating Blood Flow Restriction Training for Hamstring Injury Recovery

The Effect of Blood Flow Restriction Training on the Mechanical Properties of Hamstring Injuries: A Prospective, Randomised Clinical Trial Using Supersonic Shear Wave Elastography

Not applicable Interventional University Ghent · NCT04246515

This study is testing if Blood Flow Restriction Training can help football players recover better from recent hamstring injuries compared to regular rehab alone.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment90 (estimated)
Ages18 Years to 35 Years
SexMale
SponsorUniversity Ghent Academic / other
Locations1 site (Ghent)
Trial IDNCT04246515 on ClinicalTrials.gov

What this trial studies

This study aims to evaluate the impact of Blood Flow Restriction Training on the elasticity of the hamstring muscle following an acute injury in football players. Ninety participants aged 18 to 35 with recent hamstring strain injuries will be randomly assigned to one of three groups: classic rehabilitation with Blood Flow Restriction Training, classic rehabilitation with sham Blood Flow Restriction Training, or classic rehabilitation alone. Participants will undergo MRI scans and Shear Wave Elastography measurements to assess injury severity and muscle elasticity. The study will help determine the effectiveness of Blood Flow Restriction Training in enhancing recovery outcomes.

Who should consider this trial

Good fit: Ideal candidates are male football players aged 18 to 35 with acute hamstring strain injuries.

Not a fit: Patients with a history of hamstring injuries or contraindications for vascular occlusion will not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly improve recovery times and muscle elasticity for patients with hamstring injuries.

How similar studies have performed: Previous studies have shown promising results with Blood Flow Restriction Training in various rehabilitation contexts, suggesting potential success for this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Acute hamstring strain injury
* Male
* Adult (18+) between 18 and 35 years old

Exclusion Criteria:

* History of hamstring injuries
* Recent severe trauma or surgery in the lower extremity
* Any contra-indication for occluding vascular flow (such as hypertension, risk factors for and/or history of cardiovascular pathologies or thromboembolism, surgery, fractures, severe obesity,...)

Where this trial is running

Ghent

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Hamstring InjuryHamstring injuryShear Wave ElastographyBlood Flow Restriction
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.