Investigating blood clotting changes in meningioma surgery
Meningioma and Embolism Thrombosis Risk & Investigation of Coagulation
University Hospital Tuebingen · NCT06709833
This study looks at how blood clotting changes in patients with meningiomas during surgery to see if it affects their risk of blood clots compared to those having surgery for gliomas.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 100 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University Hospital Tuebingen (other) |
| Locations | 1 site (Tübingen, Baden-Wurttemberg) |
| Trial ID | NCT06709833 on ClinicalTrials.gov |
What this trial studies
This observational study aims to explore the coagulation and platelet function changes that occur in patients undergoing surgical resection of meningiomas, which are generally benign tumors but can lead to thrombembolic complications. Blood samples will be collected from patients before and immediately after their tumor resection to assess these changes. A control group of patients undergoing glioma resection will also be included to compare the coagulation responses. The study seeks to uncover the molecular mechanisms behind the increased thrombosis risk associated with meningiomas.
Who should consider this trial
Good fit: Ideal candidates include patients scheduled for surgical resection of meningiomas or gliomas, as well as healthy controls.
Not a fit: Patients who are not undergoing surgery for meningiomas or gliomas, or those who do not provide written consent, may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved understanding and management of thrombembolic risks in patients undergoing meningioma surgery.
How similar studies have performed: While the specific focus on meningiomas and their coagulation changes is novel, similar studies on gliomas have shown success in understanding coagulation dynamics.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients undergoing resection for meningioma or * Patients undergoing resection for glioma or * Healthy controls * written consent for study participation Exclusion Criteria: \-
Where this trial is running
Tübingen, Baden-Wurttemberg
- University Hospital for Anaesthesiology and Intensive Care Medicine, Tuebingen — Tübingen, Baden-Wurttemberg, Germany (RECRUITING)
Study contacts
- Study coordinator: Michael Koeppen, MD
- Email: michael.koeppen@med.uni-tuebingen.de
- Phone: +4970712986935
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Meningeoma, Thrombembolism, Surgical Resection, meningeoma, thrombembolism, tissue-factor