Investigating biomarkers for prognosis in polyneuropathy patients
The Prognostic Value of Blood Biomarkers for Patients With Polyneuropathy.
This study is trying to see if certain blood markers can help predict how polyneuropathy will progress in patients over time.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 200 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Rigshospitalet, Denmark Academic / other |
| Locations | 1 site (Copenhagen) |
| Trial ID | NCT06044662 on ClinicalTrials.gov |
What this trial studies
This observational study aims to explore the prognostic value of biomarkers in patients diagnosed with polyneuropathy. A prospective cohort of 200 patients will undergo physical tests, medical examinations, and blood biomarker assessments at baseline, with follow-ups at one and two years. The study will analyze the relationship between biomarker levels and disease progression using logistic regression and evaluate the diagnostic performance of these biomarkers through Receiver Operating Characteristic Curve analysis.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 18 and older who have been diagnosed with polyneuropathy confirmed by nerve conduction studies.
Not a fit: Patients who are unable to perform physical tests due to unrelated comorbidities may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide valuable insights into the prognostic factors for polyneuropathy, potentially leading to improved patient management and outcomes.
How similar studies have performed: While the use of biomarkers in polyneuropathy is an emerging area, similar studies have shown promise in other neurological conditions, suggesting potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Minimum 18 years old. * Diagnosed with polyneuropathy, confirmed by nerve conduction study. * Can read and understand Danish. Exclusion Criteria: * Inability to perform physical tests due to comorbidity not associated to the patient's polyneuropathy.
Where this trial is running
Copenhagen
- Copenhagen Neuromuscular Center, Department of Neurology, Rigshospitalet — Copenhagen, Denmark (Recruiting)
Study contacts
- Study coordinator: Tina Dysgaard, Dr.med.
- Email: Tina.dysgaard@regionh.dk
- Phone: ±45 35458077
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.