Investigating balance issues in patients with Charcot-Marie-Tooth disease
Impact of Sensory, Motor and Vestibular Deficit on the Postural Stability of CMT Patients
This study is trying to see how balance problems in people with Charcot-Marie-Tooth disease are affected by different sensory and movement issues.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 60 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | IRCCS San Raffaele Academic / other |
| Locations | 1 site (Milan) |
| Trial ID | NCT06425952 on ClinicalTrials.gov |
What this trial studies
This observational study aims to assess how sensory, motor, and vestibular deficits affect postural stability in patients with Charcot-Marie-Tooth (CMT) disease. A total of 60 participants will be recruited, including patients with CMT1A, CMT2, and various control groups with similar disabilities. The study will evaluate the relationship between neurochemical biomarkers and postural instability, providing insights for future clinical studies. By understanding these factors, the research seeks to enhance physiotherapeutic strategies for managing balance impairments in CMT patients.
Who should consider this trial
Good fit: Ideal candidates include adults aged 18 and older with a documented diagnosis of CMT, hereditary motor neuropathy, hereditary sensory neuropathy, or hereditary distal myopathy.
Not a fit: Patients who are unable to stand or have other significant neurological, psychiatric, or orthopedic disorders may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved rehabilitation strategies for patients with CMT, enhancing their balance and overall quality of life.
How similar studies have performed: While studies on balance in CMT are limited, similar approaches in other neuromuscular conditions have shown promise, indicating potential for success.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * CMT or HMN or sensory neuropathy or distal myopathy Exclusion Criteria: * unable to stand * other neurological, psychiatric, or orthopedic disorders * MMSE \<28 * alcohol abuse * intensive rehabilitation program
Where this trial is running
Milan
- Dept. of Neurology, IRCCS Ospedale San Raffaele — Milan, Italy (Recruiting)
Study contacts
- Principal investigator: Stefano C Previtali, MD — IRCCS Ospedale San Raffaele
- Study coordinator: Stefano C Previtali, MD
- Email: neuromuscolare@hsr.it
- Phone: 00390226433036
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.