Investigating arterial stiffness in sepsis patients
Official title: Arterial Stiffness as a Predictor of Acute Kidney Injury in Patients With Sepsis
Run by Assiut University · NCT06527443 · Data updated 2026-11-12
This study is testing if measuring how stiff the arteries are can help predict kidney problems in adults with sepsis.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 100 (estimated) |
| Sponsor | Assiut University Academic / other |
| Locations | 1 site (Asyut) |
| Status | Recruiting |
| Started | October 2024 |
| Main results expected | October 2026 |
| Study ends | December 2026 |
| Registry record updated | July 30, 2024 |
| Trial ID | NCT06527443 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adult patients admitted to the critical care unit with a diagnosis of sepsis.
✕Probably not a fit
Patients under 18 years old, those with end-stage renal disease, or those who cannot be scanned within 24 hours of ICU admission will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to determine if arterial stiffness, measured by Pulse Wave Velocity (PWV), is an independent risk factor for acute kidney injury in patients with sepsis. It will compare PWV with shear wave ultrasound elastography (SWE) as methods for evaluating arterial stiffness and predicting kidney injury. The study will collect demographic, clinical, and laboratory data from adult patients admitted to the critical care unit with sepsis. Comprehensive assessments will include vital signs, fluid status, and various laboratory tests to evaluate organ function.
Why it matters
Potential benefit: If successful, this study could lead to improved risk assessment and management strategies for sepsis patients, potentially reducing the incidence of acute kidney injury.
How similar studies have gone: While the specific approach of using PWV in sepsis is being explored, similar studies have shown promise in evaluating arterial stiffness as a risk factor in other conditions.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult patients who admitted to critical care unit of Internal medicine department with sepsis after obtaining consent. Exclusion Criteria: * Children below 18 yr. * Patients could not be scanned within 24-h after ICU admission. * Patients with end stage renal disease or transplanted kidney. * patients with renal artery stenosis, and obstructive uropathy
Where it's running
-
Dina Ali Hamad
Asyut, Egypt Recruiting
Study contacts
- Study coordinator: Dina A Hamad
- Email: dinaalihamad@aun.edu.eg
- Phone: +201063040703
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.