Clinical trial Recruiting at 1 site Observational Ages 18 and up

Investigating arterial stiffness in sepsis patients

Official title: Arterial Stiffness as a Predictor of Acute Kidney Injury in Patients With Sepsis

Run by Assiut University · NCT06527443 · Data updated 2026-11-12

This study is testing if measuring how stiff the arteries are can help predict kidney problems in adults with sepsis.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment100 (estimated)
SponsorAssiut University
Academic / other
Locations1 site (Asyut)
StatusRecruiting
StartedOctober 2024
Main results expectedOctober 2026
Study endsDecember 2026
Registry record updatedJuly 30, 2024
Trial IDNCT06527443 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adult patients admitted to the critical care unit with a diagnosis of sepsis.

Probably not a fit

Patients under 18 years old, those with end-stage renal disease, or those who cannot be scanned within 24 hours of ICU admission will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to determine if arterial stiffness, measured by Pulse Wave Velocity (PWV), is an independent risk factor for acute kidney injury in patients with sepsis. It will compare PWV with shear wave ultrasound elastography (SWE) as methods for evaluating arterial stiffness and predicting kidney injury. The study will collect demographic, clinical, and laboratory data from adult patients admitted to the critical care unit with sepsis. Comprehensive assessments will include vital signs, fluid status, and various laboratory tests to evaluate organ function.

Why it matters

Potential benefit: If successful, this study could lead to improved risk assessment and management strategies for sepsis patients, potentially reducing the incidence of acute kidney injury.

How similar studies have gone: While the specific approach of using PWV in sepsis is being explored, similar studies have shown promise in evaluating arterial stiffness as a risk factor in other conditions.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adult patients who admitted to critical care unit of Internal medicine department with sepsis after obtaining consent.

Exclusion Criteria:

* Children below 18 yr.
* Patients could not be scanned within 24-h after ICU admission.
* Patients with end stage renal disease or transplanted kidney.
* patients with renal artery stenosis, and obstructive uropathy

Where it's running

  • Dina Ali Hamad
    Asyut, Egypt
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
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Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.