Investigating arterial stiffness in sepsis patients
Arterial Stiffness as a Predictor of Acute Kidney Injury in Patients With Sepsis
Assiut University · NCT06527443
This study is testing if measuring how stiff the arteries are can help predict kidney problems in adults with sepsis.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 100 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Assiut University (other) |
| Locations | 1 site (Asyut) |
| Trial ID | NCT06527443 on ClinicalTrials.gov |
What this trial studies
This observational study aims to determine if arterial stiffness, measured by Pulse Wave Velocity (PWV), is an independent risk factor for acute kidney injury in patients with sepsis. It will compare PWV with shear wave ultrasound elastography (SWE) as methods for evaluating arterial stiffness and predicting kidney injury. The study will collect demographic, clinical, and laboratory data from adult patients admitted to the critical care unit with sepsis. Comprehensive assessments will include vital signs, fluid status, and various laboratory tests to evaluate organ function.
Who should consider this trial
Good fit: Ideal candidates are adult patients admitted to the critical care unit with a diagnosis of sepsis.
Not a fit: Patients under 18 years old, those with end-stage renal disease, or those who cannot be scanned within 24 hours of ICU admission will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved risk assessment and management strategies for sepsis patients, potentially reducing the incidence of acute kidney injury.
How similar studies have performed: While the specific approach of using PWV in sepsis is being explored, similar studies have shown promise in evaluating arterial stiffness as a risk factor in other conditions.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult patients who admitted to critical care unit of Internal medicine department with sepsis after obtaining consent. Exclusion Criteria: * Children below 18 yr. * Patients could not be scanned within 24-h after ICU admission. * Patients with end stage renal disease or transplanted kidney. * patients with renal artery stenosis, and obstructive uropathy
Where this trial is running
Asyut
- Dina Ali Hamad — Asyut, Egypt (RECRUITING)
Study contacts
- Study coordinator: Dina A Hamad
- Email: dinaalihamad@aun.edu.eg
- Phone: +201063040703
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: the Arterial Stiffness