Investigating a gene polymorphism's role in in-stent restenosis for coronary artery disease patients
Angiotensin Converting Enzyme rs (1799752) Gene Polymorphism and Development of In-Stent Restenosis in Patients With Stable Coronary Artery Diseases in Sohag Hospital University.
Sohag University · NCT06055673
This study is trying to see if a specific gene variation can help predict the risk of in-stent restenosis in patients with stable coronary artery disease after they have had heart procedures.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 182 (estimated) |
| Ages | 20 Years to 70 Years |
| Sex | All |
| Sponsor | Sohag University (other) |
| Locations | 1 site (Sohag) |
| Trial ID | NCT06055673 on ClinicalTrials.gov |
What this trial studies
This observational study examines the relationship between the angiotensin-converting enzyme gene polymorphism (rs1799752) and the development of in-stent restenosis (ISR) in patients with stable coronary artery disease (CAD). It utilizes DNA extraction and real-time polymerase chain reaction analysis to assess genetic factors that may contribute to ISR following percutaneous coronary intervention (PCI). The study aims to identify potential genetic markers that could help predict ISR risk in CAD patients, thereby improving patient management and outcomes.
Who should consider this trial
Good fit: Ideal candidates for this study are patients diagnosed with stable coronary artery disease.
Not a fit: Patients without any other health problems may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to better risk stratification and personalized treatment strategies for patients undergoing PCI.
How similar studies have performed: While there have been studies investigating genetic factors in ISR, this specific gene polymorphism's role in this context is less explored, making this approach somewhat novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * patients with CAD Exclusion Criteria: * PATIENTS WITHOUT OTHER HEALTH PROBLEMS
Where this trial is running
Sohag
- Sohag university Hospital — Sohag, Egypt (RECRUITING)
Study contacts
- Study coordinator: zeinab M Kadry, lecturer
- Email: zainbmahmoud@med.sohag.edu.eg
- Phone: 01225960747
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.