Invasive treatment options for complications of acute pancreatitis
Official title: Drainage and Debridement of Local Complications of Acute Pancreatitis: A Single-center Real-world Prospective Study
Run by Peking Union Medical College Hospital · NCT06023771 · Data updated 2026-11-12
This study is testing different invasive treatments for people with complications from acute pancreatitis to see how well they work and keep patients safe.
Quick facts
| Study type | Observational |
|---|---|
| Sex | All |
| Enrollment | 100 (estimated) |
| Sponsor | Peking Union Medical College Hospital Academic / other |
| Locations | 1 site (Beijing, Beijing Municipality) |
| Status | Recruiting |
| Started | October 2023 |
| Main results expected | October 2026 |
| Study ends | December 2026 |
| Registry record updated | September 5, 2023 |
| Trial ID | NCT06023771 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are patients diagnosed with acute pancreatitis who have localized complications confirmed by imaging.
✕Probably not a fit
Patients who improve with conservative treatment and do not require invasive interventions for local complications will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study focuses on evaluating the effectiveness and safety of various invasive intervention strategies for managing local complications arising from acute pancreatitis. It employs a prospective single-center cohort design to gather comprehensive clinical information and outcomes from patients undergoing these interventions. The approach emphasizes a multidisciplinary team, including specialists from internal medicine, interventional radiology, endoscopy, surgery, critical care, and nutrition, to tailor treatment strategies to individual patient needs. The study aims to assess the real-world applicability of existing intervention strategies, particularly regarding the timing and methods used.
Why it matters
Potential benefit: If successful, this study could lead to improved management strategies for patients with acute pancreatitis, potentially enhancing recovery and reducing complications.
How similar studies have gone: While there is existing evidence from randomized controlled studies, this study aims to explore the effectiveness of interventions in more complex clinical situations, making it a novel approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Admission diagnosis of acute pancreatitis; * Localized complications confirmed by imaging examinations; * Voluntary participation in the study and signing of an informed consent form. Exclusion Criteria: * Improved with conservative treatment without invasive interventions for local complications during hospitalization.
Where it's running
-
Peking Union Medical College Hospital
Beijing, Beijing Municipality, China Recruiting
Study contacts
- Principal investigator: Dong Wu — Peking Union Medical College Hospital
- Study coordinator: Dong Wu
- Email: wudong@pumch.cn
- Phone: 18612671010
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Local complications of acute pancreatitis and postoperative pancreatic fistula: what happens in real life
This multicenter registry tests how local pancreatic complications are managed in routine care and what outcomes look like over 180 days for adults.
-
SGC001 is being tested to help predicted severe acute pancreatitis
Researchers are testing SGC001 vs placebo in adults with predicted severe acute pancreatitis to see if it is safe and tolerable and to get a sense of any early effects.
-
Fecal microbiota transplant to prevent infections after late-phase severe acute pancreatitis
This trial will test whether giving healthy donor gut bacteria (fecal microbiota transplantation) through a feeding tube in the late phase of moderately severe or severe acute pancreatitis can prevent infectious complications.
-
How often splanchnic vein clots occur in acute pancreatitis and whether they relate to disease severity
This project will see if people with acute pancreatitis develop blood clots in the splenic, portal, or superior mesenteric veins and whether those clots are linked to more severe illness.
-
Fecal microbiota transplant for people with moderate to severe acute pancreatitis
This trial will test whether a fecal microbiota transplant (FMT) can reduce late complications in adults with moderate to severe acute pancreatitis.
-
Blood markers to detect infected pancreatic necrosis
We will test whether specific blood markers can help predict or diagnose infected pancreatic necrosis in adults with necrotizing pancreatitis.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.