Clinical trial Recruiting at 1 site Interventional Ages 15 to 25

Intruding upper front teeth using a utility arch plus small bone perforations

Official title: Evaluation of Dentoalveolar Changes Following Maxillary Incisor Intrusion Using Utility Arch Assisted With Micro-osteoperforations in Deep Bite Cases: A Randomized Clinical Trial

Run by Al-Azhar University · NCT07566676 · Data updated 2026-11-12

This study will test whether tiny bone perforations (micro‑osteoperforations) combined with a utility arch help move upper front teeth down in people aged 15–25 with a deep overbite.

Quick facts

Study typeInterventional
Ages15 Years to 25 Years
SexAll
Enrollment18 (estimated)
SponsorAl-Azhar University
Academic / other
Locations1 site (Cairo, Nasr City)
StatusRecruiting
StartedMay 2026
Main results expectedJune 2028
Study endsJune 2029
Registry record updatedMay 5, 2026
Trial IDNCT07566676 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are 15–25 years old with permanent dentition (excluding third molars), an overbite ≥4 mm, no prior orthodontic treatment, and good oral and periodontal health.

Probably not a fit

Patients with skeletal jaw discrepancies, missing or anomalous maxillary anterior teeth, existing root resorption, impacted canines, endodontically treated upper incisors, systemic conditions affecting tooth movement, or poor periodontal health are unlikely to benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Participants aged 15–25 with an overbite of 4 mm or more will receive maxillary incisor intrusion using a utility arch, with micro‑osteoperforations (MOPs) made through the gingiva into the cortical bone to stimulate remodeling. The MOPs are intended to increase local cytokine activity and bone resorption to speed tooth movement. Clinical and radiographic measurements will track dentoalveolar changes, intrusion amount, and signs of root resorption over the treatment period. Outcomes will compare tooth movement and root health following intrusion with the MOP‑assisted protocol.

Why it matters

Potential benefit: If successful, the approach could shorten upper‑incisor intrusion time and help limit unwanted root resorption.

How similar studies have gone: Micro‑osteoperforations are a relatively new technique and several clinical studies report modest acceleration of orthodontic tooth movement, though results on root resorption and long‑term benefit have been mixed.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Patients age between 15-25 years.
2. Patients with overbite ≥ 4 mm.
3. All permanent teeth erupted (excluding 3rd molars).
4. No previous orthodontic treatment.
5. Patients with good oral hygiene and good periodontal health.

Exclusion Criteria:

1. Skeletal discrepancies.
2. Missing maxillary anterior teeth or any kind of tooth/root shape anomaly.
3. Patients with root resorption or impacted canines.
4. Previous history of orthodontic treatment.
5. Systemic disease interferes with orthodontic tooth movement.
6. History of trauma affecting the maxillary incisors.
7. Poor oral hygiene or periodontally compromised patient.
8. Endodontically treated upper anterior teeth.

Where it's running

  • Faculty of Dental Medicine (Boys), Al-Azhar University
    Cairo, Nasr City, Egypt
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.