Intravenous contrast-enhanced ultrasound for diagnosing children's abdominal problems in China

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This multicenter observational project will perform routine abdominal ultrasound and at least one intravenous contrast-enhanced ultrasound (CEUS) in pediatric patients who need clearer intra-abdominal diagnoses. Clinicians will record imaging findings, any medical problems during CEUS, and procedural details to support development of standardized examination protocols. Data from participating hospitals will be combined into a multicenter clinical database for analysis. Clinical decisions about further care will follow CEUS results and usual clinical judgment.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Age 29 days to 18 years old;
2. The clinical diagnosis was abdominal space-occupying lesions, blunt abdominal trauma, ascites of unknown cause, and children with suspected abdominal disease but other examinations could not identify the cause.

Exclusion Criteria:

1. Allergic to sulfur hexafluoride or other components;
2. Heart disease with right-to-left shunt/severe pulmonary hypertension /uncontrolled systemic hypertension/respiratory failure/heart failure/severe arrhythmia;
3. Electrocardiogram, echocardiography or clinical manifestations of myocardial ischemia;
4. Patients with severe blood system diseases or infectious diseases;
5. Hypercoagulable state and recent history of thrombosis;
6. Severe hepatic and renal insufficiency;
7. Patients with respiratory tract infection or congenital respiratory malformation.

Where it's running

• Children's Hospital, Zhejiang University School of Medicine
  Hangzhou, Zhejiang, China Recruiting

Study contacts

• Study coordinator: YE JJ Director of the Ultrasound Department
• Email: 6195005@zju.edu.cn
• Phone: +8613868174280

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.