Interventions to improve sleep and nutrition for night shift workers
Biomarker Based Intervention Strategies to Combat Adverse Effects of Shift Work
This study is testing if personalized sleep and nutrition plans can help night shift workers feel better and improve their health compared to those who don’t get these plans.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 75 (estimated) |
| Ages | 18 Years to 60 Years |
| Sex | All |
| Sponsor | Erasmus Medical Center Academic / other |
| Locations | 1 site (Rotterdam) |
| Trial ID | NCT06147089 on ClinicalTrials.gov |
What this trial studies
This intervention focuses on testing personalized sleep and nutritional strategies to mitigate the negative health effects associated with night shift work. Participants, who are night shift workers, will undergo a three-month intervention period where they will wear smart devices, complete performance tests, and provide blood samples. The study aims to compare the health outcomes of those receiving the interventions against a control group that does not receive any intervention. The goal is to assess improvements in sleep quality and glucose regulation among participants.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18-60 who work at least four night shifts per month and have a minimum of one year of experience with shift work.
Not a fit: Patients who are pregnant, have severe psychiatric conditions, or are taking medications that may interfere with the study's objectives may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to effective strategies for improving the health and well-being of night shift workers.
How similar studies have performed: While there is limited evidence on effective interventions for night shift workers, this study explores novel personalized approaches that have not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age 18 to 60 years. * Work at least 4 night shifts a month on average. * Shift workers, working rotating shifts (morning, evening and night shifts) or working predominantly night shifts. Night shift defined as work at least 1 hours between 0:00- and 6:00. * Work at least 2 night shifts in a row * Work ≥ 20 work hours per week. * Having a shift duration of 6 h-12 h. * History of ≥ 1 year of working rotating shift work or night shifts prior to the study. Exclusion Criteria: * Taking medication that the investigator believes would interfere with the objectives of the study. For example, sleep medication, medication that interferes with glucose homeostasis, and/or anti-inflammatory drugs. * Pregnant or have a wish to become pregnant during the study period. * Planned surgery during the entire study period Alcohol consumption \> 21 units/week * Severe psychiatric disease and/or any mental or physical disability that will hinder participation in the interventions * Severe cardiovascular disease, to the discretion of the study doctor * Having a chronic inflammatory disease, including asthma, rheumatic fever, irritable bowel disease, chronic obstructive pulmonary disease. * Other bowel diseases, including Chron's disease and Colitis Ulcerosa. * A disease or condition with higher bleeding risk (/risk of hemorrhage), under which a blood sample may lead to complications. * Participation in any clinical trial including blood sampling and/or administration of substances up to 90 days before Day 01 of this study * Recent blood donation (\<1 month prior to the start of the study)
Where this trial is running
Rotterdam
- Erasmus MC — Rotterdam, Netherlands (Recruiting)
Study contacts
- Principal investigator: Heidi M Lammers-van der Holst, PhD — Erasmus Medical Center
- Study coordinator: Heidi M Lammers-van der Holst, PhD
- Email: h.lammers-vanderholst@erasmusmc.nl
- Phone: +31107043721
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.