Interventions for managing chronic migraine

Brief Behavioral Interventions for Adults With Chronic Migraine

Not applicable Interventional University of Michigan · NCT05979337

This study tests if behavioral programs like Empowered Relief and Health Education can help people with chronic migraines feel better and improve their daily lives.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment300 (estimated)
Ages18 Years and up
SexAll
SponsorUniversity of Michigan Academic / other
Locations1 site (Ann Arbor, Michigan)
Trial IDNCT05979337 on ClinicalTrials.gov

What this trial studies

This trial investigates the effects of behavioral interventions, specifically Empowered Relief and Health Education, on individuals with chronic migraine. Participants will be randomized into one of four groups and will engage in remote sessions aimed at reducing migraine-related disability and pain severity. The study focuses on whether these interventions can lead to significant improvements in daily functioning and overall quality of life for those suffering from chronic migraines.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18 and older who have a self-reported diagnosis of chronic migraine and access to the internet for remote participation.

Not a fit: Patients currently undergoing cognitive-behavioral therapy for pain or migraine may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide new, effective behavioral strategies for managing chronic migraine symptoms and improving patients' quality of life.

How similar studies have performed: Other studies have shown promise in using behavioral interventions for chronic pain management, suggesting potential success for this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Self-reported neurologist diagnosis of chronic migraine
* Meets diagnostic criteria for chronic migraine according to the Identify Chronic Migraine (IDCM) self-reported instrument
* English-speaking
* Internet access and audio-visual conferencing capability (e.g., Zoom meetings by phone or computer) in the home
* Age 18 years or older

Exclusion Criteria:

* Currently receiving cognitive-behavioral therapy for pain or migraine
* Open litigation regarding a medical condition, as assessed in preliminary study screening
* Inability to provide informed consent and complete study procedures (e.g., indications of suspected major cognitive impairment via observations of study staff during consenting) that would preclude comprehension or participation in study protocols
* Failure to complete at least 7 out of 14 pre-intervention daily diaries

Where this trial is running

Ann Arbor, Michigan

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Chronic MigraineHealth EducationMigraine-related disabilityEmpowered Relief
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.