Intervention to reduce substance-exposed pregnancies and HIV/STI risks in at-risk female teens
CHOICES-TEEN: Efficacy of a Bundled Risk Reduction Intervention for Juvenile Justice Females
NA · University of Texas at Austin · NCT05368571
This study is testing a program to help at-risk teenage girls in the juvenile justice system reduce substance use and practice safe sex to lower their chances of having substance-exposed pregnancies and getting HIV or STIs.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 400 (estimated) |
| Ages | 14 Years to 19 Years |
| Sex | Female |
| Sponsor | University of Texas at Austin (other) |
| Locations | 1 site (Houston, Texas) |
| Trial ID | NCT05368571 on ClinicalTrials.gov |
What this trial studies
The CHOICES-TEEN intervention aims to reduce the risk of substance-exposed pregnancies and HIV/STI among high-risk female youth involved with the juvenile justice system. This randomized controlled trial will compare the efficacy of the CHOICES-TEEN intervention against an attentional control group, focusing on reducing alcohol use, promoting marijuana cessation, and increasing safe sex practices. Participants will be female adolescents aged 14-19 who report specific risk behaviors, and the study will assess outcomes at 3, 6, and 9 months post-intervention. The trial will also explore cognitive self-regulation and the impact of initial readiness to change on intervention outcomes.
Who should consider this trial
Good fit: Ideal candidates for this study are female adolescents aged 14-19 who are at risk for substance-exposed pregnancies and HIV/STI due to specific sexual behaviors.
Not a fit: Patients with severe cognitive or psychiatric impairments that prevent cooperation with the study protocol will not benefit from this intervention.
Why it matters
Potential benefit: If successful, this intervention could significantly reduce the rates of substance-exposed pregnancies and sexually transmitted infections among at-risk youth.
How similar studies have performed: Previous studies have shown promise in similar behavioral interventions targeting substance use and sexual health among at-risk youth, suggesting potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: Female adolescents between 14-19 years of age, of any race, who are at risk of substance-exposed pregnancy and HIV/STI will be eligible. Specifically, they must report the following behaviors within the last 3 months: * sexual intercourse with a male * inconsistent/ineffective condom use AND * inconsistent/ineffective contraception use Exclusion Criteria: * severe cognitive and/or psychiatric impairment that precludes cooperation with study protocol, per judgement of the interventionist or research staff * do not speak or read/write in English * unable to meet study requirements, including follow-up assessments
Where this trial is running
Houston, Texas
- Baylor University — Houston, Texas, United States (RECRUITING)
Study contacts
- Principal investigator: Danielle E Parrish, Ph.D. — Baylor University
- Study coordinator: Danielle E Parrish, Ph.D.
- Email: danielle_parrish@baylor.edu
- Phone: 346-701-8047
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Risk for an Alcohol-Exposed Pregnancy, Risk for Marijuana-Exposed Pregnancy, Risk for Substance-Exposed Pregnancy, HIV Risk, Sexually Transmitted Infection Risk