Intervention for Anxiety in Toddlers

Addressing Anxiety in 2-Year-Olds: A Pilot Screening and Intervention Study

Not applicable Interventional Massachusetts General Hospital · NCT04039243

This study is testing a new online therapy program for parents and their toddlers aged 2-3 who are feeling anxious to see if it helps reduce their fear and shyness.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment90 (estimated)
Ages21 Months to 47 Months
SexAll
SponsorMassachusetts General Hospital Academic / other
Locations1 site (Boston, Massachusetts)
Trial IDNCT04039243 on ClinicalTrials.gov

What this trial studies

This study aims to evaluate the feasibility and effectiveness of a parent-child Cognitive Behavioral Therapy (CBT) intervention for 2-3-year-old children exhibiting elevated levels of fear, shyness, or anxiety. The intervention, called 'Being Brave,' involves remote sessions with parents and their children to help reduce anxiety symptoms. The study will assess the impact of this intervention on anxiety levels and follow up with participants one year later to determine the sustainability of the results.

Who should consider this trial

Good fit: Ideal candidates for this study are 2-3-year-old children with elevated temperamental fear or shyness, or diagnosed anxiety, along with their English-speaking parents.

Not a fit: Children with Autism Spectrum Disorder, severe disruptive behaviors, or other primary disorders that make CBT inappropriate will not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could significantly reduce anxiety symptoms in young children, improving their emotional well-being and development.

How similar studies have performed: Other studies have shown promising results with CBT interventions for anxiety in young children, indicating that this approach is both viable and potentially effective.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* The child scores \>1 Standard Deviation (SD) above reported means for the Fear or Shyness scales on the Early Childhood Behavior Questionnaire (ECBQ) (if child is 21-35 months) or the child scores \>1SD above reported means for the Total Anxiety, Generalized Anxiety, Social Anxiety, Physical Injury Fears, or Separation Anxiety scales on the Preschool Anxiety Scale (PAS) (if child is 36-47 months) as completed by a parent
* The parents are able to speak, understand, and read English
* The child must have a working knowledge of English.

Exclusion Criteria:

* Autism Spectrum Disorder (ASD) or global developmental delay in the child
* The child has disruptive behavior so severe as to interfere with participation in intervention sessions
* The child has a different primary disorder for which CBT for anxiety is inappropriate (e.g. severe depression, depression in the mother, significant medical disorder).

Where this trial is running

Boston, Massachusetts

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Anxiety Disorder of ChildhoodFearShynessAnxiety disordersToddlersPreschoolersCognitive-behavioral therapy
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.