Interval exercise for veterans with COPD and sleep apnea

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effects of moderate intensity interval training (MIIT) on functional outcomes in veterans diagnosed with both chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea (OSA), a condition known as Overlap Syndrome. The research aims to address the unique challenges faced by veterans with excessive daytime sleepiness associated with this syndrome, who are at a higher risk for functional decline. By evaluating participation in life situations, physical activity, and cardiovascular health, the study seeks to develop tailored exercise strategies that can improve the quality of life for these patients. The ultimate goal is to reduce the risk of functional decline through increased physical activity.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Diagnosis of COPD and OSA, i.e., Overlap Syndrome Diagnosis of Overlap Syndrome (both COPD and OSA), confirmed in CPRS from spirometry or pulmonary function test of FEV1/FVC \<70 for COPD and a polysomnogram or home-based study for OSA.
* Montreal Cognitive Assessment (MoCA) \>20

Exclusion Criteria:

* CAD, as defined by anyone of the following: history of CABG, prior positive stress test for ischemia, infarction or angina or medical problem
* Orthopedic problems as defined by joint pain limiting ambulation
* Fall risk, defined as more than 2 falls in the prior month
* Hospitalization in prior month
* Daytime home oxygen 6. Participation in structured exercise, defined by the Physical Activity Scale for the Elderly (PASE) as more than 1 hour of activity spent in moderate activity and any strenuous activity performed over prior 7 days.

Where it's running

• Salem VA Medical Center, Salem, VA
  Salem, Virginia, United States Recruiting

Study contacts

• Principal investigator: Madalina Macrea, MD PhD — Salem VA Medical Center, Salem, VA
• Study coordinator: Madalina Macrea, MD PhD
• Email: Madalina.Macrea@va.gov

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.