Interval exercise for veterans with COPD and sleep apnea
The Effect of Interval Exercise on Functional Outcomes in Veterans With COPD and OSA
NA · VA Office of Research and Development · NCT05254431
This study is testing if moderate exercise can help veterans with both COPD and sleep apnea feel better and improve their daily activities.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 28 (estimated) |
| Sex | All |
| Sponsor | VA Office of Research and Development (fed) |
| Locations | 1 site (Salem, Virginia) |
| Trial ID | NCT05254431 on ClinicalTrials.gov |
What this trial studies
This study investigates the effects of moderate intensity interval training (MIIT) on functional outcomes in veterans diagnosed with both chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea (OSA), a condition known as Overlap Syndrome. The research aims to address the unique challenges faced by veterans with excessive daytime sleepiness associated with this syndrome, who are at a higher risk for functional decline. By evaluating participation in life situations, physical activity, and cardiovascular health, the study seeks to develop tailored exercise strategies that can improve the quality of life for these patients. The ultimate goal is to reduce the risk of functional decline through increased physical activity.
Who should consider this trial
Good fit: Ideal candidates for this study are veterans diagnosed with both COPD and OSA, specifically those experiencing excessive daytime sleepiness.
Not a fit: Patients with coronary artery disease, significant orthopedic problems, or those who have recently been hospitalized may not benefit from this study.
Why it matters
Potential benefit: If successful, this intervention could significantly improve the functional outcomes and quality of life for veterans suffering from both COPD and OSA.
How similar studies have performed: While the approach of using interval exercise in this specific population is novel, similar studies have shown positive outcomes in improving functional status in patients with chronic respiratory conditions.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Diagnosis of COPD and OSA, i.e., Overlap Syndrome Diagnosis of Overlap Syndrome (both COPD and OSA), confirmed in CPRS from spirometry or pulmonary function test of FEV1/FVC \<70 for COPD and a polysomnogram or home-based study for OSA. * Montreal Cognitive Assessment (MoCA) \>20 Exclusion Criteria: * CAD, as defined by anyone of the following: history of CABG, prior positive stress test for ischemia, infarction or angina or medical problem * Orthopedic problems as defined by joint pain limiting ambulation * Fall risk, defined as more than 2 falls in the prior month * Hospitalization in prior month * Daytime home oxygen 6. Participation in structured exercise, defined by the Physical Activity Scale for the Elderly (PASE) as more than 1 hour of activity spent in moderate activity and any strenuous activity performed over prior 7 days.
Where this trial is running
Salem, Virginia
- Salem VA Medical Center, Salem, VA — Salem, Virginia, United States (RECRUITING)
Study contacts
- Principal investigator: Madalina Macrea, MD PhD — Salem VA Medical Center, Salem, VA
- Study coordinator: Madalina Macrea, MD PhD
- Email: Madalina.Macrea@va.gov
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: COPD, OSA, Overlap Syndrome