Internet-based physical activity program for cognitive speed in multiple sclerosis
Internet-Delivered Lifestyle Physical Activity Intervention for Cognitive Processing Speed in Multiple Sclerosis
This study is testing whether an online exercise program can help people with multiple sclerosis think faster and improve their overall quality of life.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 280 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University of Illinois at Chicago Academic / other |
| Locations | 1 site (Chicago, Illinois) |
| Trial ID | NCT04518657 on ClinicalTrials.gov |
What this trial studies
This trial investigates the effects of an Internet-delivered physical activity intervention on cognitive processing speed in individuals with multiple sclerosis (MS). It is a randomized controlled trial comparing the intervention to an active control condition, focusing on improving cognitive function, learning, memory, and quality of life. Participants will engage in a structured program designed to increase their physical activity levels while being monitored remotely. The study aims to provide robust evidence on the efficacy of this behavioral approach for managing cognitive impairments associated with MS.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and older with a diagnosis of multiple sclerosis who are currently physically inactive and able to ambulate without assistance.
Not a fit: Patients with moderate to high risk for injury during physical activity or those not meeting the inclusion criteria may not benefit from this study.
Why it matters
Potential benefit: If successful, this intervention could significantly improve cognitive processing speed and overall quality of life for patients with multiple sclerosis.
How similar studies have performed: Previous pilot studies have shown promising results for similar Internet-delivered physical activity interventions in improving cognitive function in MS patients.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Residing in the United States (residing in Alabama is not required) * English as primary language * Between 18+ years old * Diagnosis of MS * Relapse free in the past 30 days * Internet and email access * Currently physically inactive (GLTEQ) * Able to ambulate without assistance (self-report and PDDS) * Willingness to complete the questionnaires * Willingness to wear the accelerometer * Willingness to undergo random assignment (BIPAMS or WellMS) Exclusion Criteria: * Individuals not meeting above inclusion criteria * Individuals with moderate to high risk for contraindications of possible injury or death when undertaking strenuous or maximal exercise (PARQ)
Where this trial is running
Chicago, Illinois
- University of Illinois at Chicago — Chicago, Illinois, United States (Recruiting)
Study contacts
- Principal investigator: Robert W Motl, PhD — University of Illinois at Chicago
- Study coordinator: Robert W Motl, Ph.D
- Email: robmotl@uic.edu
- Phone: 312 413-7850
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.