International Pediatric Peritoneal Biobank

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to collect peritoneal membrane biopsies from children undergoing peritoneal dialysis to investigate morphological changes and complications associated with the treatment. Biopsies will be taken during catheter insertion, abdominal surgeries, or renal transplantation. The research will analyze tissue characteristics and correlate them with treatment modalities and patient outcomes, providing insights into the unique pediatric population. This observational study seeks to fill the knowledge gap regarding peritoneal dialysis effects in children.

Why it matters

Who can join: the full rules

Inclusion Criteria

* Age 0 to 90 years
* CKD 5D, peritoneal dialysis and
* Patients with normal renal function and elective abdominal surgery due to limited abdominal pathology (such as hernia repair, gallstones….)
* Patients post PD and post Tx
* Oral and written consent
* Ability to consent of the adult patient and of the parents and legal guardian of patients not yet of legal age, respectively

Exclusion Criteria:

* Abdominal adhesions, malformation and inflammation beyond PD induced changes
* Patients with disseminated tumour disease
* Patients with critical heart failure and other medical conditions, where the additional procedure may confer an increased increase risk
* Pregnancy
* Preterm babies (below 37 weeks of gestational age)
* Serum hemoglobin \< 10 g/dl in newborns and \< 8 g/dl in children and adults

Where it's running

• Children's Mercy Hospital
  Kansas City, Missouri, United States Recruiting
• Department of Pediatrics, Medical University Vienna
  Vienna, Austria Recruiting
• UZ Ghent
  Ghent, Belgium Recruiting
• University Children's Hospital
  Prague, Czechia Recruiting
• Service de Néphrologie Pédiatrique, Hôpital Femme Mere Enfant
  Lyon, France Recruiting
• University Children's Hospital
  Strasbourg, France Recruiting

Study contacts

• Principal investigator: Claus P Schmitt, MD — University of Heidelberg, Center for Pediatric and Adolescent Medicine
• Study coordinator: Claus P Schmitt, Prof
• Email: claus.peter.schmitt@med.uni-heidelberg.de
• Phone: +49 6221 56

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.