Intensive training to improve finger movement after stroke

The Effect of Intensive Training on Recovery of Fingers Dexterity Following Stroke: Behavioral, Physiological and Anatomical Predictors

Phase1; Phase2 Interventional Loewenstein Hospital · NCT04229329

This study tests if intensive finger training can help stroke survivors improve their finger movement and coordination during recovery.

Quick facts

PhasePhase1; Phase2
Study typeInterventional
Enrollment70 (estimated)
Ages20 Years to 85 Years
SexAll
SponsorLoewenstein Hospital Academic / other
Locations1 site (Raanana)
Trial IDNCT04229329 on ClinicalTrials.gov

What this trial studies

This study investigates the effects of intensive finger individuation training on the recovery of dexterous movement in patients who have experienced a stroke. The approach focuses on providing targeted therapy during the critical subacute phase of recovery, aiming to enhance upper-limb motor function. Participants will undergo intensive therapy sessions designed to improve finger movement and coordination, with the goal of achieving clinically meaningful improvements in dexterity.

Who should consider this trial

Good fit: Ideal candidates are individuals who have experienced their first symptomatic ischemic or hemorrhagic stroke and have a clinically evident upper-limb motor deficit.

Not a fit: Patients with other neurological or psychiatric conditions affecting motor function, or those with orthopedic issues that hinder participation, may not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could significantly enhance the recovery of hand function in stroke patients, leading to improved quality of life.

How similar studies have performed: While similar approaches have been explored, this specific intensive training method during the subacute phase is relatively novel and has not been extensively tested.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* First symptomatic ischemic or hemorrhagic stroke
* Clinically evident upper-limb motor deficit
* Understand the study aim, is able to cooperate with the task for the specified time
* Clinically stable

Exclusion Criteria:

* Other neurological or psychiatric illness which affects upper-limb motor function
* An orthopedic or rheumatologic disease that affects the ability to undergo a robotic hand therapy.
* Sensory problems that prevent the patient from reporting pain during the robotic hand therapy
* Skin breakdown or wounds located in places where the hand contacts the robot.
* Patients with C/I to TMS (history of seizures, the existence of cardiac pacer, VP shunt, spinal stimulator or any other hardware that may malfunction at the presence of strong magnetic fields) will no undergo TMS but may participate in the study
* Participation in another interventional study for upper limb rehabilitation

Where this trial is running

Raanana

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Stroke
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.