Intensive rehabilitation after minimally invasive lung resection
Official title: Interest of Intensive Postoperative Rehabilitation Following Minimally Invasive Lung Resection: A Randomized Controlled Study
Run by University Hospital, Rouen · NCT06202222 · Data updated 2026-11-12
This project tests whether intensive postoperative rehabilitation helps people with non-small cell lung cancer recover faster and spend less time in hospital after minimally invasive lung resection.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 184 (estimated) |
| Sponsor | University Hospital, Rouen Academic / other |
| Locations | 3 sites (Valenciennes, Hauts-de-France and 2 other locations) |
| Status | Recruiting |
| Started | September 9, 2024 |
| Main results expected | May 9, 2027 |
| Study ends | May 9, 2027 |
| Registry record updated | September 10, 2025 |
| Trial ID | NCT06202222 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are people with non-small cell lung cancer scheduled for major minimally invasive lung resection who can perform the chair-rise test and tolerate cycling-based exercises.
✕Probably not a fit
Patients with contraindications to cyclo-ergometry (for example recent DVT, lower-limb amputation, severe musculoskeletal or skin issues), a Glasgow score under 15, or those not having minimally invasive resection are unlikely to benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The trial enrolls patients with diagnosed or suspected non-small cell lung cancer scheduled for major lung resection via a minimally invasive approach. Participants receive a structured, intensive postoperative physiotherapy program—drawing on techniques used in COPD rehabilitation—with daily sessions starting on the day of surgery and functional exercises such as chair-rise testing and cycling where appropriate. Patients with contraindications to cyclo-ergometry or severe lower-limb/skin conditions are excluded. Key outcomes include respiratory function, postoperative complications, and length of hospital stay.
Why it matters
Potential benefit: If successful, the program could improve postoperative respiratory function, reduce complications, and shorten hospital stays after minimally invasive lung resection.
How similar studies have gone: Previous prehabilitation and perioperative rehabilitation programs adapted from COPD care have shown improved exercise capacity and some reductions in complications, but standardized intensive postoperative protocols remain less well validated.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients requiring surgery for diagnosed or undergoing diagnosis of lung cancer. * Patients in need of major lung resection through a minimally invasive approach. * Patients capable of performing the chair rise test. Exclusion Criteria: \- Contraindications to cyclo-ergometry: Deep vein thrombosis in a lower limb. Patients with one or both lower limbs amputated. Rheumatological pathology, trauma, or previous surgery in the lower limb, pelvis, or spine, resulting in limited joint amplitude or strict immobilization. Dermatological conditions with severe lesions preventing prolonged sitting on a bicycle. * Glasgow score less than 15. * Patients who have not undergone pulmonary resection by minimally invasive surgery. * Patients hospitalized outside the thoracic surgery department before the first post-operative visit with the physiotherapist on Day 0.
Where it's running
-
Valenciennes, Hospital
Valenciennes, Hauts-de-France, France Recruiting -
CAEN, university Hospital
Caen, Normandy, France Recruiting -
Rouen, University Hospital
Rouen, Normandy, France Recruiting
Study contacts
- Study coordinator: Jean-Marc BASTE, PhD
- Email: jean-marc.baste@chu-rouen.fr
- Phone: +33 2 32 88 87 04
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.