Inspiratory muscle training at different intensities and intercostal muscle oxygenation

Investigation of the Acute Effect of Inspiratory Muscle Training Applied at Different Intensities on Intercostal Muscle Oxygenation

This test sees if short inspiratory muscle training sessions at 0%, 30%, or 70% of maximal inspiratory pressure change oxygen levels in the intercostal muscles of healthy, physically active adults.

Quick facts

• Phase: Not applicable
• Study type: Interventional
• Enrollment: 27 (estimated)
• Ages: 18 Years to 35 Years
• Sex: All
• Sponsor: Kirsehir Ahi Evran Universitesi (Academic / other)
• Locations: 1 site (Kırşehir)
• Trial ID: NCT07029074 on ClinicalTrials.gov

What this trial studies

This interventional study measures how short bouts of inspiratory muscle training at three intensities (sham 0%, 30% MIP, and 70% MIP) acutely affect oxygen saturation in the intercostal muscles of healthy, physically active adults. Participants perform controlled inspiratory efforts while investigators record intercostal muscle oxygenation with noninvasive monitoring and use maximal inspiratory pressure to set the training intensities. People with chronic or systemic disease, a heavy smoking history, recent infection, or psychiatric disorders are excluded. The work is conducted at the cardiopulmonary unit of Kırşehir Ahi Evran University and focuses on immediate physiological responses rather than long-term training adaptations.

Who should consider this trial

Good fit: Ideal candidates are healthy, physically active adults who exercise at moderate intensity at least 3 days per week and have no chronic or systemic disease.

Not a fit: Individuals with diagnosed chronic respiratory or systemic disease, heavy smokers (≥10 pack‑years), recent infections, or psychiatric conditions were excluded and may not benefit from these healthy-subject findings.

Why it matters

Potential benefit: If successful, the results could help refine inspiratory muscle training settings to better preserve muscle oxygenation and reduce respiratory fatigue, informing protocols for people with breathing limitations.

How similar studies have performed: Prior studies have shown inspiratory muscle training can increase inspiratory strength and affect blood flow to respiratory muscles, but acute effects of different intensities on intercostal muscle oxygenation are less well established.

Eligibility criteria

Inclusion Criteria:

* Physically active (doing moderate intensity physical activity for at least 3 days a week for 150 minutes / week)
* Volunteer to participate in the study

Exclusion Criteria:

* Healthy individuals with any diagnosed chronic or systemic disease,
* Smoke 10 packs x years or more,
* Pneumonia or any acute infection,
* Psychiatric disorder will excluded in the study.

Where this trial is running

Kırşehir

• Kırşehir Ahi Evran University, Physical Therapy and Rehabilitation Center, Cardiopulmonary Unit — Kırşehir, Turkey (Türkiye) (Recruiting)

Study contacts

• Study coordinator: Başak KAVALCI KOL, PhD

Conditions Healthy; muscle oxygenation; inspiratory muscle training; intercostal muscle