Injectable versus mono-thread PLLA for atrophic acne scars

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

In a prospective split-face design, 24 adult patients with Goodman and Baron grade 2–4 atrophic acne scars received PLLA mono-threads on the right side (single session) and injectable PLLA on the left side (two sessions six weeks apart). Clinical outcomes, dermal remodeling, and safety were followed for three months using Goodman and Baron qualitative and quantitative grading systems. The study compares effects on scar appearance, collagen stimulation, and skin physiology between the two delivery modalities. Adverse events and tolerability were monitored for each side.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* included adult patients (≥18 years) of both sexes presenting with clinically diagnosed atrophic acne scars (Grades 2-4 according to the Goodman and Baron classification)

Exclusion Criteria:

* active acne lesions, pregnancy or lactation, bleeding disorders, keloid tendency, systemic diseases affecting wound healing, recent acne scar treatment within the past six months, and known hypersensitivity to PLLA components.

Where it's running

• Zagazig University Hospitals
  Zagazig, Sharqia Province, Egypt Recruiting

Study contacts

• Study coordinator: Reham Essam, MD
• Email: rereessam22@gmail.com
• Phone: +201097709477

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.