Infusion of stem cells from umbilical cords for treating cerebral palsy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This trial investigates the safety and efficacy of intravenous infusion of cultured allogeneic adult umbilical cord derived mesenchymal stem cells (UC-MSCs) in patients diagnosed with cerebral palsy (CP). Participants will receive a single infusion of 100 million UC-MSCs and will be monitored for safety and efficacy at various intervals over a period of 48 months. The study aims to provide insights into the potential benefits of stem cell therapy for individuals with CP.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Diagnosis of Cerebral Palsy

Exclusion Criteria:

* Active infection
* Active cancer
* Chronic multisystem organ failure
* Pregnancy
* Clinically significant Abnormalities on pre-treatment laboratory evaluation
* Medical condition that would (based on the opinion of the investigator) compromise patient's safety
* Previous organ transplant
* Seizure disorder
* Hypersensitivity to sulfur

Where it's running

• Prodromos Stem Cell Institute
  Naples, Florida, United States Recruiting
• Prodromos Stem Cell Institute
  Athens, Greece Recruiting

Study contacts

• Principal investigator: Chadwick Prodromos, MD — The Foundation for Orthopaedics and Regenerative Medicine

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Sensory Integration Therapy vs Conventional Physical Therapy in Children With Mixed Cerebral Palsy

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• Multisite upper limb surgery in children with unilateral cerebral palsy

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• Spinal Stimulation During Walking to See If Spasticity Lessens in Cerebral Palsy

  This study tests whether walking with non-invasive spinal stimulation reduces leg muscle tightness and improves walking in children and young adults with cerebral palsy.

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• Combined leg nerve blocks for kids with cerebral palsy after surgery

  This study tests whether adding two nerve blocks to standard anesthesia helps control pain in children with cerebral palsy after lower limb surgery.

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• Smartphone gait checks for kids with unilateral spastic CP

  This study tests whether a phone’s accelerometer can reliably measure walking in children with unilateral spastic cerebral palsy.

  Recruiting Deraya University · Minya, Menia Governorate · NCT07730086

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.