Information-sharing about breast arterial calcification after mammography

Enhancing the Public Health Benefits of Mammography Screening by Informing Women of Both Breast Cancer and Breast Arterial Calcification Results: a Randomized Trial to Promote Cardiovascular Health

NA · Icahn School of Medicine at Mount Sinai · NCT04983875

This study is testing if giving women extra information about their breast arterial calcification results along with their mammogram results helps them understand their health better.

Quick facts

PhaseNA
Study typeInterventional
Enrollment14875 (estimated)
Ages40 Years and up
SexFemale
SponsorIcahn School of Medicine at Mount Sinai (other)
Locations1 site (New York, New York)
Trial IDNCT04983875 on ClinicalTrials.gov

What this trial studies

This study aims to evaluate the benefits of providing women with information about their breast arterial calcification (BAC) results alongside standard mammography results. The research will involve a diverse group of 14,875 women scheduled for mammography at Mount Sinai's breast radiology clinics. Participants will receive either a BAC-enhanced letter or be placed in a waitlist control group to assess the impact of this additional information on patient awareness and health outcomes. The study seeks to address the gap in communication regarding BAC, which may be linked to coronary artery disease.

Who should consider this trial

Good fit: Ideal candidates are women aged 40 and older who are scheduled for mammography and can read and speak English or Spanish.

Not a fit: Patients with known coronary artery disease or significant cardiovascular conditions may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance patient awareness and potentially lead to better cardiovascular health outcomes for women.

How similar studies have performed: Previous studies have indicated a desire among patients for more information regarding BAC, suggesting potential for success in this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria

* Female
* Scheduled to undergo mammography at one of Mount Sinai's breast radiology clinics (e.g., Dubin Breast Center, Radiology Associates)
* Age ≥ 40 years
* Read and speak English or Spanish
* Ability to understand and the willingness to sign a written informed consent
* Willing to sign and date any applicable medical record release documents for the study

Exclusion Criteria:

* Participants with known coronary artery disease (via self-report)
* Previous physician-diagnosed heart attack, stroke or TIA, heart failure, angina or taking nitroglycerin, or atrial fibrillation (via self-report or review of EMR)
* Inability to understand and comply with the instructions of the study due to the presence of cognitive or psychiatric conditions (such as dementia, psychosis, or mania), compromising ability to provide informed consent and/or follow study procedures
* Pregnant women

Where this trial is running

New York, New York

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Mammography, Vascular Calcification, Breast Arterial Calcification, Women's Health, Preventive Medicine, Behavioral Medicine, Screening

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.