Clinical trial Recruiting at 1 site Interventional Ages 20 and up

Individualized rTMS for improving motor recovery in stroke patients

Official title: Efficacy of Individualized Repetitive Transcranial Magnetic Stimulation Based on Cortical Laterality for Motor Recovery in Stroke Patients

Run by National Taiwan University Hospital · NCT05914038 · Data updated 2026-11-12

This study is testing if a personalized brain stimulation treatment can help stroke patients recover better and improve their movement within three months of their stroke.

Quick facts

Study typeInterventional
Ages20 Years and up
SexAll
Enrollment40 (estimated)
SponsorNational Taiwan University Hospital
Academic / other
Locations1 site (Taipei County, Taipei)
StatusRecruiting
StartedOctober 13, 2023
Main results expectedMay 20, 2025
Study endsMay 20, 2027
Registry record updatedOctober 18, 2024
Trial IDNCT05914038 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adults over 20 who have experienced a unilateral ischemic or hemorrhagic stroke within the last three months and have limited upper limb strength.

Probably not a fit

Patients with a history of previous strokes, significant neurological disorders, or contraindications to rTMS may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effectiveness of individualized repetitive transcranial magnetic stimulation (rTMS) tailored to the lateralization index in enhancing motor recovery and cortical excitability in patients who have experienced a stroke. The approach utilizes both high and low-frequency rTMS to modulate cerebral cortex excitability, with a focus on subacute stroke patients within three months of their event. Unlike previous studies that applied a uniform rTMS protocol, this study aims to personalize treatment based on individual patient characteristics. The goal is to determine if this tailored approach can lead to better recovery outcomes.

Why it matters

Potential benefit: If successful, this study could provide a more effective treatment option for motor recovery in stroke patients.

How similar studies have gone: While traditional rTMS has been studied in stroke rehabilitation, this individualized approach based on lateralization index is novel and has not been extensively tested.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Unilateral ischemic or hemorrhagic stroke
2. Stroke within 3 months
3. Medical Research Council Scale for Muscle Strength in upper limb ≤ 3
4. No previous stroke, seizure, dementia, Parkinson's disease or other degenerative neurological diseases.
5. Patient could sit over 15 minutes
6. Age over 20

Exclusion Criteria:

1. Previous stroke, traumatic brain injury, brain tumor
2. With central nervous system disease (spinal cord injury, Parkinson's disease)
3. Any contraindication to rTMS (seizure, alcoholism, metal implant, pacemaker)
4. Patients unable to cooperate the treatment
5. Pregnancy
6. Depression

Where it's running

  • National Taiwan University Hospital
    Taipei County, Taipei, Taiwan
    Recruiting

Study contacts

  • Principal investigator: Meng Ting Lin, M.D. — The Department of Physical Medicine and Rehabilitation, National Taiwan University Hospital
  • Study coordinator: Meng Ting Lin, M.D.
  • Email: b96401093@ntu.edu.tw
  • Phone: +886-2312-3456

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.