Individualized cognitive training for heart failure patients
A Multicenter Randomized Single-blinded Clinical Trial to Investigate the Effects of a Home-based Cognitive Training for individualS Affected bY chroNic heArt Failure: an Individualized Program to increaSE Cognitive Functions
This study tests if a personalized home-based brain training program can help improve memory and thinking skills in older adults with heart failure.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 54 (estimated) |
| Ages | 50 Years and up |
| Sex | All |
| Sponsor | Montreal Heart Institute Academic / other |
| Locations | 2 sites (Montréal, Quebec and 1 other locations) |
| Trial ID | NCT05223426 on ClinicalTrials.gov |
What this trial studies
The SYNAPSE trial evaluates the impact of a personalized home-based cognitive training program on cognitive functions in patients with heart failure. This intervention aims to improve memory and executive functions, which are often impaired in heart failure patients, thereby enhancing their overall well-being. The study targets adults aged 50 and older who have chronic heart failure and can engage in cognitive training. By providing an alternative to traditional rehabilitation programs, the trial seeks to reduce dropout rates and improve patient outcomes. The findings could lead to better tailored care for heart failure patients experiencing cognitive deficits.
Who should consider this trial
Good fit: Ideal candidates are adults aged 50 or older with chronic heart failure who have access to the internet and can engage in cognitive training.
Not a fit: Patients with recent acute cardiovascular events, uncontrolled diabetes, or neurological diseases may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly enhance cognitive function and quality of life for heart failure patients.
How similar studies have performed: While cognitive training has shown effectiveness in older adults, its application in heart failure patients is still underexplored, making this approach relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult aged 50 or older * Have access to Internet * Have access to a computer or a tablet; * Have the ability to perform cognitive training; * Have the ability to read, understand and consent to the informed consent form; * Have chronic heart failure on tolerated therapy for at least two months; * Without limitation of physical activity to severe limitation of physical activity (i.e. NYHA class I, class II, class III OR class IV). Exclusion Criteria: * Acute cardiovascular event 1 month before randomization; * Cardiovascular procedure scheduled within 3 months; * Uncontrolled diabetes or untreated thyroid dysfunction; * Current or recent malignancy with a life expectancy of less than 1 year; * Neurological disease; * Chronic hemodialysis or peritoneal dialysis.
Where this trial is running
Montréal, Quebec and 1 other locations
- Preventive medicine and physical activity center (centre EPIC), Montreal heart Institute — Montréal, Quebec, Canada (Not_yet_recruiting)
- Centre de recherche du centre Hospitalier de l'Université de Montréal (CRCHUM) — Montréal, Quebec, Canada (Recruiting)
Study contacts
- Principal investigator: Louis Bherer, PhD — Montreal Heart Institute
- Study coordinator: Louis Bherer, PhD
- Email: louis.bherer@umontreal.ca
- Phone: 514-376-3330
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.