Increasing physical exercise and education to help manage endometriosis

Adapted Physical Activity as Complementary Treatment to Alleviate the Symptoms of Endometriosis? The CRESCENDO Program (inCRease Physical Exercise and Sport to Combat ENDOmetriosis)

Not applicable Interventional Upper Alsace University · NCT05831735

This study is testing if a program that includes exercise and education can help women with endometriosis feel better and improve their quality of life, while also looking at how it affects their relationships.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment200 (estimated)
Ages18 Years to 60 Years
SexAll
SponsorUpper Alsace University Academic / other
Locations1 site (Mulhouse, Escriva-Boulley)
Trial IDNCT05831735 on ClinicalTrials.gov

What this trial studies

This program aims to explore the effects of adapted physical activity (APA) on women with endometriosis, focusing on their psychological and social well-being. Participants will engage in physical activity and educational sessions delivered via videoconferencing, addressing the barriers and facilitators to exercise in the context of endometriosis. The study seeks to establish a causal link between physical activity and improvements in symptoms and quality of life for those affected by this chronic condition. By involving life-partners, the program also aims to gain insights into the broader impact of endometriosis on interpersonal relationships.

Who should consider this trial

Good fit: Ideal candidates include sexually active individuals aged 18 and older with confirmed endometriosis who experience moderate to significant pain and functional difficulties.

Not a fit: Patients with other disabling diseases, a BMI over 35, or those not experiencing major difficulties related to endometriosis may not benefit from this program.

Why it matters

Potential benefit: If successful, this program could significantly improve the quality of life and psychological well-being of patients suffering from endometriosis.

How similar studies have performed: While studies on the link between physical activity and endometriosis are limited, the beneficial effects of adapted physical activity on chronic diseases suggest potential for success in this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* 18 years,
* sexually active,
* having endometriosis confirmed by laparoscopy or MRI (or saliva test if approved by health authorities),
* reporting moderate to significant functional difficulties and pain (between 4 and 10 / 10 points on visual analogue scale), and
* having free access to the internet to participate in the APA and TPE sessions, and fill in the questionnaires.

Exclusion Criteria:

* having a disabling disease other than endometriosis (cancer, fibromyalgia, arthritis, ...),
* a BMI higher than 35,
* not experiencing major difficulties related to the disease,
* having surgery or Medically Assisted Procreation scheduled within 9 months.

Where this trial is running

Mulhouse, Escriva-Boulley

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions EndometriosisQuality of Lifeendometriosis,physical activity,education,painvideoconferencing
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.