Increasing exercise in people with multiple sclerosis through physical therapy
Promotion of Exercise for Multiple Sclerosis Through Physical Therapy (PromPT)
This study is testing a new physical therapy program to see if it can help people with multiple sclerosis become more active and improve their quality of life.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 40 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University of Michigan Academic / other |
| Locations | 1 site (Ann Arbor, Michigan) |
| Trial ID | NCT06933160 on ClinicalTrials.gov |
What this trial studies
This pilot study evaluates a consultative physical therapy intervention aimed at increasing physical activity among individuals with multiple sclerosis (MS). It involves a randomized controlled trial comparing the effects of the intervention against a waitlist control group, focusing on feasibility metrics and accelerometer-measured physical activity levels. The study targets individuals who are not sufficiently active and assesses the immediate and sustained effects of the physical therapy model. The goal is to enhance engagement in physical activity, which is crucial for managing MS symptoms and improving quality of life.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and older with a clinical diagnosis of multiple sclerosis who are currently not sufficiently active.
Not a fit: Patients with severe cognitive impairments or those unable to attend study visits may not benefit from this study.
Why it matters
Potential benefit: If successful, this intervention could significantly improve physical activity levels and overall quality of life for patients with multiple sclerosis.
How similar studies have performed: Previous studies have shown positive outcomes in increasing physical activity among MS patients through similar interventions, indicating potential for success.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Clinical diagnosis of MS * 18 years and older * Able to read and speak English sufficiently to allow for informed consent and active participation in the intervention sessions * Relapse free for the past 30 days * Willingness to attend all study visits and PT sessions for the duration of study * Access to a smartphone * Not sufficiently active as measured by the Godin Leisure Time Exercise Questionnaire score \<24 * Patient Determined Disease Steps score 0-3 or the ability to ambulate either independently or with the use of a cane (or similar device) for at least 75% of the time at baseline * Less than 2 affirmative on the physical activity readiness questionnaire Exclusion Criteria: * Inability to provide informed consent (e.g., cognitive impairment, unable to sufficiently communicate in English) * Unable to attend study visits * Any impairment, activity, behavior, or situation that in the judgment of the study team would prevent satisfactory completion of the study protocol.
Where this trial is running
Ann Arbor, Michigan
- University of Michigan — Ann Arbor, Michigan, United States (Recruiting)
Study contacts
- Principal investigator: Dominique Kinnett-Hopkins, PhD — University of Michigan
- Study coordinator: Dominique Kinnett-Hopkins
- Email: dlkh@umich.edu
- Phone: 734-647-5424
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.