Increasing access to PrEP for trans women in the Deep South
T'Cher, Take Charge: Increasing PrEP Awareness, Uptake and Adherence Through Health Care Empowerment and Addressing Social Determinants of Health Among Racially Diverse Trans Women in the Deep South
This study is testing if providing support from peers can help trans women in the Deep South access and stick with PrEP to prevent HIV.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 200 (estimated) |
| Ages | 18 Years and up |
| Sex | Female |
| Sponsor | CrescentCare Academic / other |
| Locations | 1 site (New Orleans, Louisiana) |
| Trial ID | NCT05689281 on ClinicalTrials.gov |
What this trial studies
This intervention aims to enhance the uptake and adherence of PrEP among trans women by addressing barriers and facilitators through a stepped wedge design. Participants will receive peer navigation support to encourage their engagement with PrEP services. The study will also evaluate the impact of health care empowerment and social determinants of health on the effectiveness of the intervention. By comparing outcomes between the intervention and delayed study arms, the research seeks to identify effective strategies for improving PrEP access in this population.
Who should consider this trial
Good fit: Ideal candidates for this study are trans women aged 18 and older who are HIV uninfected and reside in the New Orleans metropolitan area.
Not a fit: Patients who are confirmed HIV positive or currently participating in another PrEP-related study may not benefit from this intervention.
Why it matters
Potential benefit: If successful, this intervention could significantly increase PrEP uptake and adherence among trans women, reducing their risk of HIV infection.
How similar studies have performed: Other studies have shown success in improving PrEP uptake through peer navigation and targeted interventions, indicating a promising approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Provision of signed and dated informed consent form * Declaration of willingness to comply with all study procedures and availability during the study * Age 18 years old or older * Male sex designated at birth * Identify as trans woman, woman or another gender identity not associated with being a man * Desire to use or re-start PrEP * HIV uninfected * Speaks English or Spanish * Live in the New Orleans metropolitan statistical area (which includes 8 parishes) Exclusion Criteria: * Confirmed HIV infection by rapid algorithm testing and/or laboratory testing (described above) * Prior or current participation in the active arm of an HIV vaccine trial with evidence of vaccine-induced seropositivity * Concurrent or planned enrollment in a research study that provides PrEP * Unwilling to attend quarterly follow-up visits, which will include survey participation * Has any other condition which, based on the opinion of the investigator, would preclude provision of informed consent; make participation in the project unsafe; complicate interpretation of outcome data; or otherwise interfere with achieving the project objectives
Where this trial is running
New Orleans, Louisiana
- NO/AIDS Task Force d.b.a. CrescentCare — New Orleans, Louisiana, United States (Recruiting)
Study contacts
- Study coordinator: Narquis Barak, MS
- Email: narquis.barak@crescentcare.org
- Phone: 504.821.2601
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.