Impulse oscillometry for better asthma monitoring

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a longitudinal observational study enrolling adults with asthma who have a planned change in maintenance therapy. Participants undergo baseline and follow-up visits over 3–6 months with full lung function testing (including FEV1), multiple breath nitrogen washout, impulse oscillometry (IOS), and questionnaires (ACT, ACQ, AQLQ). The study compares changes in IOS parameters versus FEV1, stratified by changes in patient-reported control and quality of life, and examines whether proposed minimal clinically important differences are valid over short follow-up intervals. No investigational drug is given; the protocol observes real-world treatment changes and corresponding physiological and questionnaire outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adult asthma patients with a scheduled consultation at the outpatient hospital to whom a step-up or step-down of their pharmacological asthma treatment is prescribed

Exclusion Criteria:

* Unstable asthma (defined as need for oral corticosteroids or (respiratory) antibiotic course in the 4 weeks before inclusion or any major medical issue in the 4 weeks before inclusion)

Where it's running

• Universitair Ziekenhuis Brussel
  Brussels, Belgium Recruiting

Study contacts

• Study coordinator: Shane Hanon, Prof. Dr. MD.
• Email: Shane.Hanon@uzbrussel.be
• Phone: 02 477 6841

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.