Clinical trial Recruiting at 1 site Interventional Ages 20 and up

Improving walking symmetry after stroke with treadmill resistance and sensory feedback

Official title: Optimizing Post-Stroke Gait Symmetry: Integrating Mechanical Constraints and Sensory Feedback to Enhance Paretic Leg Propulsion

Run by The University of Texas Medical Branch, Galveston · NCT07087769 · Data updated 2026-11-12

This one-time test tries treadmill resistance plus real-time visual or auditory feedback to see if it improves leg push-off and walking symmetry in adults who had a stroke, compared with healthy adults.

More Stroke trials

Quick facts

Study typeInterventional
Ages20 Years and up
SexAll
Enrollment30 (estimated)
SponsorThe University of Texas Medical Branch, Galveston
Academic / other
Locations1 site (Galveston, Texas)
StatusRecruiting
StartedJuly 25, 2025
Main results expectedDecember 1, 2026
Study endsDecember 1, 2026
Registry record updatedApril 1, 2026
Trial IDNCT07087769 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults aged 20 or older who had a clinical stroke at least one month ago and can walk at least 10 meters with or without an assistive device are ideal candidates.

Probably not a fit

People with progressive neurological disease, severe cognitive impairment or dementia, unstable cardiac conditions, recent lower-limb amputation, major musculoskeletal problems affecting gait, or poorly controlled medical conditions are unlikely to benefit or be eligible.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This single-session protocol enrolls 15 adults post-stroke and 15 healthy adults to compare walking under tied-belt and split-belt treadmill conditions. Investigators apply backward-directed mechanical resistance at the pelvis, ankle, or both, and provide real-time visual, auditory, or combined sensory feedback, delivered alone or in combination. The goal is to identify which mechanical and sensory environment best increases paretic leg propulsion and propulsion symmetry. Sessions take about one to two hours, use non-invasive equipment, and carry minimal risk aside from rare, mild skin irritation from sensors.

Why it matters

Potential benefit: If successful, the protocol could reveal specific treadmill and feedback combinations that improve paretic leg propulsion and help clinicians tailor gait training to restore more symmetrical walking after stroke.

How similar studies have gone: Previous studies using split-belt treadmills and targeted sensory feedback have shown promise for improving gait symmetry after stroke, though combining mechanical constraints with multisensory feedback in a single-session protocol is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

Aged 20 years or older

For stroke group: clinical diagnosis of stroke at least 1 month prior to participation

Ability to walk at least 10 meters with or without assistive devices

For healthy group: able to walk independently without assistive devices

Exclusion Criteria:

Life expectancy less than one year

Comatose or unable to follow three-step commands

Amputation of any lower limb

Poorly controlled diabetes (e.g., foot ulceration)

Blindness

Progressive neurological disease

Medically unstable condition

Significant musculoskeletal impairments affecting gait

Congestive heart failure or unstable angina

Peripheral vascular disease

Severe neuropsychiatric conditions (e.g., dementia, cognitive deficits, severe depression)

Where it's running

  • University of Texas Medical Branch
    Galveston, Texas, United States
    Recruiting

Study contacts

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.