Improving walking recovery in patients with muscle weakness from critical illness

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effects of rehabilitation using Functional Electrical Stimulation (FES) on the motor performance of critically ill patients suffering from Critical Illness Myopathy (CIM) and Critical Illness Polyneuropathy (CIP). It aims to distinguish which variant benefits more from FES-based rehabilitation and to identify biomarkers associated with walking recovery. The study will involve a longitudinal clinical trial comparing rehabilitation protocols with and without FES. The hypothesis is that voluntary muscle activation during electrical stimulation will enhance rehabilitation outcomes.

Why it matters

Who can join: the full rules

Critical Illness Patient Inclusion Criteria:

* clinical diagnosis of tetra/paraparesis of peripheral origin as disclosed by ENG/EMG examination;
* be independent before the episode of critical illness

Critical Illness Patient Exclusion Criteria:

* history of previous comorbidity for ICU-AW;
* previous known chronic polyneuropathy;
* severe coagulopathy;
* severe disorder of consciousness;
* contraindications to Electrical Stimulation application

Healthy Subjects Exclusion Criteria:

* Prosthetic implants
* musculoskeletal, neurological, cardiovascular and pulmonary disorders that may alter the gait

Where it's running

• IRCCS Fondazione Don Carlo Gnocchi Onlus
  Milan, Italy Recruiting

Study contacts

• Study coordinator: Tiziana Lencioni
• Email: tlencioni@dongnocchi.it
• Phone: 00390240308547

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• High-tech rehabilitation program for adults with acute neuromuscular disease

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• Observing recovery from weakness after severe respiratory and cardiac failure

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• Tracking muscle changes over time in ICU patients with sepsis.

  We will try to track muscle strength and size over time in people with sepsis in the ICU using bedside exams, ultrasounds, and electrical tests.

  Recruiting Centre Hospitalier de Saint-Brieuc · Saint-Brieuc · NCT07074028

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.