Improving visual comfort for patients with visual impairment using special contact lenses

Managing Visual Comfort and Function in Patients With Low Vision Using Acuvue Oasys

NA · Nova Southeastern University · NCT05829135

This study is testing special contact lenses that change with light to see if they can make daily life easier for people with visual impairments.

Quick facts

PhaseNA
Study typeInterventional
Enrollment16 (estimated)
Ages18 Years to 64 Years
SexAll
SponsorNova Southeastern University (other)
Locations1 site (Davie, Florida)
Trial IDNCT05829135 on ClinicalTrials.gov

What this trial studies

This study evaluates the effectiveness of Acuvue Oasys Contact Lenses with Transitions Light Intelligent Technology in enhancing visual comfort for individuals with visual impairments. The lenses are designed to adapt to varying light conditions, reducing glare and light sensitivity. Participants will be assessed to determine if these lenses can significantly improve their daily living activities affected by visual discomfort. The study aims to provide insights into how adaptive lens technology can benefit those with specific ocular conditions.

Who should consider this trial

Good fit: Ideal candidates include individuals with a confirmed diagnosis of ocular conditions such as Stargardt's, Cone dystrophy, or Retinitis Pigmentosa who experience glare and light sensitivity.

Not a fit: Patients who are pregnant, nursing, or have recent ocular infections or surgeries may not benefit from this study.

Why it matters

Potential benefit: If successful, this could significantly enhance the quality of life for patients suffering from visual impairments by reducing glare and improving visual comfort.

How similar studies have performed: While the specific use of these lenses for visual impairment is novel, similar adaptive lens technologies have shown promise in improving visual comfort in other populations.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Ability to give informed consent
* Able to speak and read English
* Experience glare and light sensitivity that impacts patient's daily living activities
* Have confirmed diagnosis of ocular condition including but not limited to Stargardt's, Cone dystrophy, Cone-rod dystrophy, Albinism, Retinitis Pigmentosa and Achromatopsia.
* Willing and able to wear the contact lenses as instructed

Exclusion Criteria:

* Are pregnant, nursing or planning to become pregnant during the course of the study
* Have current/recent ocular infection, inflammation, surgery in the past 3 months that contraindicates contact lens wear

Where this trial is running

Davie, Florida

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Photophobia, Visual Impairment, Low Vision

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.