Improving vagina laxity with a new formulation

Safety and Efficacy of Formulation Containing Stem Cell Secretome and Liquorice Root Extract for Improving Vagina Laxity of Women in Malaysia: A Pilot Study.

NA · Ungku Shahrin Medical Aesthetic Research & Innovation (USMARI) Centre · NCT05710536

This study is testing a new treatment made from natural ingredients to see if it can help women aged 40 to 55 improve vaginal tightness.

Quick facts

PhaseNA
Study typeInterventional
Enrollment18 (estimated)
Ages40 Years to 55 Years
SexFemale
SponsorUngku Shahrin Medical Aesthetic Research & Innovation (USMARI) Centre (industry)
Locations1 site (Petaling Jaya, Selangor)
Trial IDNCT05710536 on ClinicalTrials.gov

What this trial studies

This pilot study investigates the safety and efficacy of a formulation containing stem cell secretome and licorice root extract aimed at improving vagina laxity in Malaysian women aged 40 to 55. Over a duration of 5 weeks, participants will undergo assessments at baseline, week 2, and week 5 to evaluate changes in vagina laxity and monitor any adverse effects. The formulation is designed to stimulate cell rejuvenation and promote cell renewal through a blend of natural polypeptides and plant extracts.

Who should consider this trial

Good fit: Ideal candidates are Malaysian women aged 40 to 55 who are experiencing complaints of vagina laxity.

Not a fit: Patients who are pregnant, breastfeeding, or have undergone recent procedures for vagina laxity may not benefit from this study.

Why it matters

Potential benefit: If successful, this formulation could provide a non-invasive option for women experiencing vagina laxity, enhancing their quality of life.

How similar studies have performed: While this approach is novel, similar studies exploring the use of natural formulations for vaginal health have shown promising results.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Malaysian women ( age 40 to 55 years old)
* Complaint of vagina laxity
* Willingness to participate in the study

Exclusion Criteria:

* Pregnant and breastfeeding women
* Doing any surgical or non-surgical procedures to improved vaginal laxity condition such as laser and radiofrequency before participating in the study that might affect the study outcome
* Presence of illness or taking any medication that might impact the study outcome or participants well-being

Where this trial is running

Petaling Jaya, Selangor

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Healthy, Vagina laxity

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.