Improving tic control in youth with chronic tic disorders

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study focuses on the effectiveness of Comprehensive Behavioral Intervention for Tics (CBIT) in treating chronic tic disorders in youth aged 12-21. Participants will learn to manage their tics through competing response training, which involves applying alternative motor actions to inhibit tics. The study aims to evaluate the impact of this behavioral therapy on tic severity and overall functioning. By assessing the outcomes, the research seeks to enhance the understanding of tic management in this population.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age 12-21 years at time of enrollment.
* Current chronic motor and/or vocal tics, defined as tics for at least 1 year without a tic-free period of more than 3 consecutive months. Tics must not be due to a medical condition or the direct physiological effects of a substance.
* At least moderate tic severity, defined as a Yale Global Tic Severity Scale total score

  ≥14 (≥9 for those with motor or vocal tics only).
* Full scale IQ greater than 70
* English fluency to ensure comprehension of study measures and instructions.

Exclusion Criteria:

* Active suicidality.
* Previous diagnosis of psychosis or cognitive disability.
* Substance abuse or dependence within the past year.
* Concurrent psychotherapy focused on tics.
* Neuroleptic/antipsychotic medications.
* Taking a medication that has not reached stability criterion (same medication and dose for 6 weeks with no planned changes over the intervention period)

Where it's running

• University of Minnesota
  Minneapolis, Minnesota, United States Recruiting

Study contacts

• Principal investigator: Christine Conelea, PhD — University of Minnesota
• Study coordinator: Brianna Wellen, PhD
• Phone: 6126265472

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.