Improving tic control in youth with chronic tic disorders
Modeling Tic Change During Behavior Therapy for Tics
This study is testing whether a new therapy can help young people aged 12-21 manage their tics better and improve their daily life.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 30 (estimated) |
| Ages | 12 Years to 21 Years |
| Sex | All |
| Sponsor | University of Minnesota Academic / other |
| Locations | 1 site (Minneapolis, Minnesota) |
| Trial ID | NCT06270251 on ClinicalTrials.gov |
What this trial studies
This study focuses on the effectiveness of Comprehensive Behavioral Intervention for Tics (CBIT) in treating chronic tic disorders in youth aged 12-21. Participants will learn to manage their tics through competing response training, which involves applying alternative motor actions to inhibit tics. The study aims to evaluate the impact of this behavioral therapy on tic severity and overall functioning. By assessing the outcomes, the research seeks to enhance the understanding of tic management in this population.
Who should consider this trial
Good fit: Ideal candidates are youth aged 12-21 with chronic motor and/or vocal tics of moderate severity.
Not a fit: Patients with active suicidality, psychosis, or those currently undergoing psychotherapy for tics may not benefit from this study.
Why it matters
Potential benefit: If successful, this intervention could significantly improve tic control and quality of life for patients with chronic tic disorders.
How similar studies have performed: Previous studies have shown that CBIT is effective in reducing tic severity, indicating a promising approach for this intervention.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age 12-21 years at time of enrollment. * Current chronic motor and/or vocal tics, defined as tics for at least 1 year without a tic-free period of more than 3 consecutive months. Tics must not be due to a medical condition or the direct physiological effects of a substance. * At least moderate tic severity, defined as a Yale Global Tic Severity Scale total score ≥14 (≥9 for those with motor or vocal tics only). * Full scale IQ greater than 70 * English fluency to ensure comprehension of study measures and instructions. Exclusion Criteria: * Active suicidality. * Previous diagnosis of psychosis or cognitive disability. * Substance abuse or dependence within the past year. * Concurrent psychotherapy focused on tics. * Neuroleptic/antipsychotic medications. * Taking a medication that has not reached stability criterion (same medication and dose for 6 weeks with no planned changes over the intervention period)
Where this trial is running
Minneapolis, Minnesota
- University of Minnesota — Minneapolis, Minnesota, United States (Recruiting)
Study contacts
- Principal investigator: Christine Conelea, PhD — University of Minnesota
- Study coordinator: Brianna Wellen, PhD
- Phone: 6126265472
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.